Detailed information NTG1110431

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACODFA_RS29300
• Genome accession: NZ_CP184642
• Coordinates: 6188529..6189866 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 0211
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 6183529..6194866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACODFA_RS29275 (ACODFA_29275)	pgeF	6183672..6184400 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
ACODFA_RS29280 (ACODFA_29280)	rluD	6184397..6185359 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACODFA_RS29285 (ACODFA_29285)	-	6185505..6186530 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
ACODFA_RS29290 (ACODFA_29290)	-	6186687..6186932 (+)	246	WP_014603563.1	PP0621 family protein	-
ACODFA_RS29295 (ACODFA_29295)	pilS	6186922..6188514 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACODFA_RS29300 (ACODFA_29300)	pilR	6188529..6189866 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACODFA_RS29305 (ACODFA_29305)	thiO	6189912..6191006 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
ACODFA_RS29310 (ACODFA_29310)	-	6191141..6191650 (+)	510	WP_015503652.1	GspH/FimT family pseudopilin	-
ACODFA_RS29315 (ACODFA_29315)	-	6191756..6192262 (+)	507	WP_003094696.1	GspH/FimT family pseudopilin	-
ACODFA_RS29320 (ACODFA_29320)	pilV	6192253..6192810 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
ACODFA_RS29325 (ACODFA_29325)	pilW	6192807..6193631 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
ACODFA_RS29330 (ACODFA_29330)	pilX	6193628..6194215 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1110431 ACODFA_RS29300 WP_003094694.1 6188529..6189866(+) (pilR) [Pseudomonas aeruginosa strain 0211]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1110431 ACODFA_RS29300 WP_003094694.1 6188529..6189866(+) (pilR) [Pseudomonas aeruginosa strain 0211]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384