Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V3C22_RS08615 Genome accession   NZ_CP183775
Coordinates   1755041..1755733 (-) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1750041..1760733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS08590 (V3C22_08590) - 1750100..1750726 (-) 627 WP_002268642.1 hypothetical protein -
  V3C22_RS08595 (V3C22_08595) der 1750801..1752111 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  V3C22_RS08600 (V3C22_08600) dnaI 1752124..1753023 (-) 900 WP_002284744.1 primosomal protein DnaI -
  V3C22_RS08605 (V3C22_08605) - 1753024..1754193 (-) 1170 WP_002295603.1 DnaD domain protein -
  V3C22_RS08610 (V3C22_08610) nrdR 1754180..1754671 (-) 492 WP_002295602.1 transcriptional regulator NrdR -
  V3C22_RS08615 (V3C22_08615) covR 1755041..1755733 (-) 693 WP_002262121.1 response regulator GcrR Regulator
  V3C22_RS08620 (V3C22_08620) - 1756089..1756625 (-) 537 WP_002295601.1 DUF177 domain-containing protein -
  V3C22_RS08625 (V3C22_08625) - 1756618..1757193 (-) 576 WP_226706726.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -
  V3C22_RS08630 (V3C22_08630) - 1757301..1758008 (+) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  V3C22_RS08635 (V3C22_08635) - 1758010..1760622 (+) 2613 WP_002295600.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=1105967 V3C22_RS08615 WP_002262121.1 1755041..1755733(-) (covR) [Streptococcus mutans strain Xc]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1105967 V3C22_RS08615 WP_002262121.1 1755041..1755733(-) (covR) [Streptococcus mutans strain Xc]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment