Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V3C22_RS05310 Genome accession   NZ_CP183775
Coordinates   1107918..1109225 (-) Length   435 a.a.
NCBI ID   WP_002264510.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1102918..1114225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS05280 (V3C22_05280) - 1103466..1103936 (-) 471 WP_012997758.1 cytidine deaminase -
  V3C22_RS05285 (V3C22_05285) deoC 1103842..1104504 (-) 663 WP_002262220.1 deoxyribose-phosphate aldolase -
  V3C22_RS05290 (V3C22_05290) - 1104523..1105800 (-) 1278 WP_226708870.1 pyrimidine-nucleoside phosphorylase -
  V3C22_RS05295 (V3C22_05295) - 1105909..1106505 (-) 597 WP_002302498.1 class I SAM-dependent methyltransferase -
  V3C22_RS05300 (V3C22_05300) coaA 1106601..1107521 (+) 921 WP_002262217.1 type I pantothenate kinase -
  V3C22_RS05305 (V3C22_05305) rpsT 1107575..1107829 (+) 255 WP_011074586.1 30S ribosomal protein S20 -
  V3C22_RS05310 (V3C22_05310) ciaH 1107918..1109225 (-) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  V3C22_RS05315 (V3C22_05315) ciaR 1109215..1109889 (-) 675 WP_002264509.1 three-component system response regulator CiaR Regulator
  V3C22_RS05320 (V3C22_05320) ciaX 1109940..1110203 (-) 264 WP_002268040.1 three-component system regulator CiaX -
  V3C22_RS05325 (V3C22_05325) - 1110604..1113153 (-) 2550 WP_226708869.1 M1 family aminopeptidase -
  V3C22_RS05330 (V3C22_05330) phoU 1113194..1113847 (-) 654 WP_002262211.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49856.29 Da        Isoelectric Point: 9.7262

>NTDB_id=1105945 V3C22_RS05310 WP_002264510.1 1107918..1109225(-) (ciaH) [Streptococcus mutans strain Xc]
MLIKLRKQKQDENISFFSHFFAVFTGIFFVMTVIIIQVMHFGIYSSVDNSLKIATENVNDYVNMTLSHNNPITEAENGDA
SFKVKSNGQMAANTDTILYDKKHNVINNVNAFSSLYHIRPKLKDIGDIVEQEAKNIYGQTEKYRTVTVKVNNDFYPQIKF
ATIVINTTQLEEANTRYVTIIISVMIVFWLISVIASVYLAKWSQKPILENYEKQKSFVENASHELRTPLAVLQNRLESLF
RKPEATILDSSESIASSLEEVRNMRMLTANLLNLARRDDGIKPEITEIQPRFFDDTFKNYEMIARENGKKLHITNKVNRQ
IKTDKTLLKQLMTILFDNAVKYTDNDGEIWLDVKTTDRSLIFSVADNGQGISDEDKKKIFDRFYRVDKARTRQKGGFGLG
LSLAKQITDSLKGSIIVKDKKPQGVMFEARLLANK

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=1105945 V3C22_RS05310 WP_002264510.1 1107918..1109225(-) (ciaH) [Streptococcus mutans strain Xc]
ATGCTAATTAAATTAAGAAAACAAAAGCAGGATGAGAATATTTCATTTTTCAGTCATTTCTTTGCTGTTTTTACCGGAAT
ATTCTTTGTTATGACAGTTATTATTATTCAGGTTATGCATTTTGGTATCTATTCTTCAGTTGATAATAGTCTAAAAATAG
CAACTGAGAATGTCAATGATTATGTCAATATGACTCTATCGCATAATAATCCTATTACTGAAGCTGAAAATGGAGATGCC
TCTTTTAAAGTAAAATCAAATGGCCAGATGGCTGCTAATACAGATACTATTCTTTATGATAAAAAGCATAACGTCATCAA
TAATGTCAATGCCTTCTCTTCTTTGTATCATATTCGCCCTAAACTAAAAGATATTGGTGATATTGTTGAACAAGAAGCTA
AGAATATTTACGGTCAGACCGAAAAGTATCGGACAGTGACAGTTAAGGTAAATAATGATTTTTACCCACAGATAAAATTT
GCAACGATTGTTATTAATACAACACAGCTTGAAGAGGCTAATACGCGTTATGTTACGATTATTATCAGTGTGATGATTGT
TTTTTGGCTTATATCAGTTATTGCCAGTGTTTATTTAGCGAAGTGGAGTCAAAAACCGATTCTGGAAAATTATGAAAAGC
AAAAATCATTTGTTGAAAATGCTAGTCATGAATTACGTACTCCTTTGGCTGTTTTACAAAATCGCTTGGAGAGTTTGTTT
CGAAAACCAGAGGCTACTATCTTAGATTCTTCGGAATCTATTGCTTCTAGTTTGGAAGAGGTCAGAAACATGAGAATGCT
GACAGCAAATCTCCTTAATTTAGCCCGTCGGGATGATGGTATCAAACCAGAAATAACAGAAATTCAACCTCGTTTTTTTG
ATGATACTTTTAAAAATTATGAGATGATCGCTCGAGAAAATGGGAAAAAATTGCATATTACCAATAAGGTCAACCGTCAA
ATTAAGACAGATAAGACTTTGCTGAAGCAATTAATGACTATTCTTTTTGATAATGCTGTCAAATATACAGATAACGACGG
GGAAATTTGGCTGGACGTCAAGACAACTGATCGCAGTTTAATTTTTTCAGTTGCGGACAATGGTCAAGGTATTTCAGACG
AGGATAAGAAGAAAATTTTTGATCGTTTTTATCGCGTCGATAAAGCCAGAACACGACAAAAGGGTGGGTTCGGACTTGGT
TTGTCTTTGGCAAAACAAATAACAGACAGCTTAAAAGGCAGCATTATTGTTAAAGATAAAAAACCACAAGGAGTAATGTT
TGAAGCTCGCCTGCTTGCTAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

99.77

100

0.998
  ciaH Streptococcus pneumoniae Rx1

55.632

100

0.556
  ciaH Streptococcus pneumoniae D39

55.632

100

0.556
  ciaH Streptococcus pneumoniae R6

55.632

100

0.556
  ciaH Streptococcus pneumoniae TIGR4

55.632

100

0.556

Multiple sequence alignment