Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   ACM67B_RS02085 Genome accession   NZ_CP181247
Coordinates   421878..422732 (+) Length   284 a.a.
NCBI ID   WP_416189949.1    Uniprot ID   -
Organism   Neisseria sp. CCUG17229     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 416878..427732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM67B_RS02065 (ACM67B_02065) - 417666..418232 (-) 567 WP_416189947.1 hypothetical protein -
  ACM67B_RS02075 (ACM67B_02075) pilF 418891..420567 (+) 1677 WP_416189948.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACM67B_RS02080 (ACM67B_02080) pilG 420635..421876 (+) 1242 WP_416190494.1 type II secretion system F family protein Machinery gene
  ACM67B_RS02085 (ACM67B_02085) pilD 421878..422732 (+) 855 WP_416189949.1 prepilin peptidase Machinery gene
  ACM67B_RS02090 (ACM67B_02090) coaE 422742..423350 (+) 609 WP_416189950.1 dephospho-CoA kinase -
  ACM67B_RS02095 (ACM67B_02095) yacG 423353..423538 (+) 186 WP_095501899.1 DNA gyrase inhibitor YacG -
  ACM67B_RS02100 (ACM67B_02100) ispH 423620..424588 (-) 969 WP_416189951.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  ACM67B_RS02105 (ACM67B_02105) lspA 424613..425113 (-) 501 WP_416189952.1 signal peptidase II -

Sequence

Protein


Download         Length: 284 a.a.        Molecular weight: 31296.29 Da        Isoelectric Point: 7.5821

>NTDB_id=1099563 ACM67B_RS02085 WP_416189949.1 421878..422732(+) (pilD) [Neisseria sp. CCUG17229]
MLETWNALAPFVVPLAVIFGLLIGSFLNVVIYRVPVMMERGWTQFAKEHLNVPLTAEEEAPFTLSKPDSRCPQCHAPVKA
WQNVPIVSYLLLGGKCSSCKTPISIRYPLVELLTGILFGVVAWQYGWSWLTFGGLIFTAMLVALTFIDYDTQYLPDSLTL
PLVWLGLLYNYNGTFTTLQSAVLGAVCGYMSLWLLCYVYKLLTGKIGMGGGDFKLLAALGAWLGVDVLPILVFMAALIGI
IGALVSRVAKGQPFAFGPSLAVVGWVIFITNEPIHQLIQWWLTK

Nucleotide


Download         Length: 855 bp        

>NTDB_id=1099563 ACM67B_RS02085 WP_416189949.1 421878..422732(+) (pilD) [Neisseria sp. CCUG17229]
ATGCTGGAAACTTGGAATGCCTTAGCGCCGTTTGTTGTGCCATTGGCGGTGATTTTCGGTTTGTTAATCGGCAGCTTTTT
GAATGTGGTGATTTATCGTGTGCCAGTCATGATGGAGCGCGGTTGGACGCAGTTTGCTAAAGAGCATTTGAATGTGCCGC
TTACGGCCGAAGAAGAAGCACCGTTTACATTGTCAAAACCTGATTCACGCTGTCCGCAATGTCATGCGCCGGTGAAGGCT
TGGCAGAATGTTCCGATTGTGAGTTACTTGCTGTTGGGTGGCAAATGTAGTTCGTGTAAAACGCCCATCAGCATCCGTTA
TCCTTTAGTGGAATTACTTACCGGCATCTTATTTGGTGTTGTGGCATGGCAATACGGCTGGTCGTGGCTGACATTTGGTG
GCTTGATTTTCACTGCCATGTTGGTGGCGCTCACTTTTATCGACTACGATACCCAATATCTGCCCGATTCCCTAACTCTG
CCGCTGGTGTGGCTGGGTTTACTGTATAACTACAACGGCACATTTACCACGTTGCAATCGGCGGTGTTGGGCGCAGTGTG
CGGTTATATGAGTTTGTGGTTGCTGTGTTATGTCTATAAACTCTTAACCGGTAAAATCGGCATGGGTGGTGGCGACTTTA
AATTATTGGCTGCACTGGGTGCATGGCTAGGTGTGGACGTATTGCCGATATTGGTGTTTATGGCAGCATTAATCGGCATT
ATCGGCGCGCTTGTATCGCGGGTTGCTAAAGGGCAGCCATTTGCCTTTGGCCCAAGCTTGGCGGTGGTCGGATGGGTTAT
TTTCATTACCAATGAACCGATTCACCAATTGATTCAATGGTGGTTAACGAAATGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(18-125)

Type IV leader peptidase family (Peptidase_A24)

(136-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

70.251

98.239

0.69
  pilD Acinetobacter nosocomialis M2

49.231

91.549

0.451
  pilD Vibrio cholerae strain A1552

45.714

98.592

0.451
  pilD Vibrio campbellii strain DS40M4

45.848

97.535

0.447
  pilD Acinetobacter baumannii D1279779

48.462

91.549

0.444

Multiple sequence alignment