Detailed information NTG1098147

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACM59W_RS26955
• Genome accession: NZ_CP181089
• Coordinates: 5663607..5664944 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain ST175LTH
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5658607..5669944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM59W_RS26930 (ACM59W_26930)	pgeF	5658750..5659478 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACM59W_RS26935 (ACM59W_26935)	rluD	5659475..5660437 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACM59W_RS26940 (ACM59W_26940)	-	5660583..5661608 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACM59W_RS26945 (ACM59W_26945)	-	5661765..5662010 (+)	246	WP_003102591.1	PP0621 family protein	-
ACM59W_RS26950 (ACM59W_26950)	pilS	5662000..5663592 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACM59W_RS26955 (ACM59W_26955)	pilR	5663607..5664944 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACM59W_RS26960 (ACM59W_26960)	thiO	5664990..5666084 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
ACM59W_RS26965 (ACM59W_26965)	-	5666219..5666728 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
ACM59W_RS26970 (ACM59W_26970)	-	5666834..5667340 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
ACM59W_RS26975 (ACM59W_26975)	pilV	5667331..5667888 (+)	558	WP_003102600.1	type 4a pilus minor pilin PilV	Machinery gene
ACM59W_RS26980 (ACM59W_26980)	pilW	5667885..5668709 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACM59W_RS26985 (ACM59W_26985)	pilX	5668706..5669293 (+)	588	WP_003102605.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1098147 ACM59W_RS26955 WP_003094694.1 5663607..5664944(+) (pilR) [Pseudomonas aeruginosa strain ST175LTH]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1098147 ACM59W_RS26955 WP_003094694.1 5663607..5664944(+) (pilR) [Pseudomonas aeruginosa strain ST175LTH]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384