Detailed information NTG1097398

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACM3H0_RS03375
• Genome accession: NZ_CP180685
• Coordinates: 628371..630608 (-)
• Length: 745 a.a.
• NCBI ID: WP_000939916.1
• Uniprot ID: A0AAW6XU20
• Organism: Streptococcus agalactiae strain M14
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 623371..635608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM3H0_RS03350 (ACM3H0_03350)	holA	623435..624472 (-)	1038	WP_000560292.1	DNA polymerase III subunit delta	-
ACM3H0_RS03355 (ACM3H0_03355)	-	624526..625254 (-)	729	WP_000468965.1	class I SAM-dependent methyltransferase	-
ACM3H0_RS03360 (ACM3H0_03360)	-	625430..626422 (+)	993	WP_000800994.1	alpha/beta hydrolase fold domain-containing protein	-
ACM3H0_RS03365 (ACM3H0_03365)	-	626481..627425 (-)	945	WP_000200825.1	LacI family DNA-binding transcriptional regulator	-
ACM3H0_RS03370 (ACM3H0_03370)	-	627436..628245 (-)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
ACM3H0_RS03375 (ACM3H0_03375)	comEC/celB	628371..630608 (-)	2238	WP_000939916.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACM3H0_RS03380 (ACM3H0_03380)	-	630592..631245 (-)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
ACM3H0_RS03385 (ACM3H0_03385)	-	631343..632083 (-)	741	WP_000500220.1	lysophospholipid acyltransferase family protein	-
ACM3H0_RS03390 (ACM3H0_03390)	-	632218..632982 (+)	765	WP_416055449.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ACM3H0_RS03395 (ACM3H0_03395)	-	632975..633241 (+)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
ACM3H0_RS03400 (ACM3H0_03400)	-	633426..635012 (-)	1587	WP_000673088.1	DEAD/DEAH box helicase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85548.47 Da
• Isoelectric Point: 9.7741

>NTDB_id=1097398 ACM3H0_RS03375 WP_000939916.1 628371..630608(-) (comEC/celB) [Streptococcus agalactiae strain M14]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLGCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=1097398 ACM3H0_RS03375 WP_000939916.1 628371..630608(-) (comEC/celB) [Streptococcus agalactiae strain M14]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTATACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAGGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTTTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

• Competence protein (Competence) (215-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.469	100	0.489
comEC/celB	Streptococcus mitis NCTC 12261	48.267	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.004	100	0.474
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC	Lactococcus lactis subsp. cremoris KW2	44.145	99.732	0.44