Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   ACGHT2_RS10005 Genome accession   NZ_AP031455
Coordinates   1913255..1913986 (-) Length   243 a.a.
NCBI ID   WP_058692509.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain k46-0107-A9     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1908255..1918986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGHT2_RS09970 (K460107A9_18740) - 1909407..1909607 (-) 201 WP_058692506.1 hypothetical protein -
  ACGHT2_RS09975 (K460107A9_18750) - 1909816..1910157 (-) 342 WP_195990867.1 bacteriocin immunity protein -
  ACGHT2_RS09980 (K460107A9_18760) - 1910208..1910435 (-) 228 WP_048791098.1 hypothetical protein -
  ACGHT2_RS09985 (K460107A9_18770) - 1910708..1911019 (-) 312 WP_048791097.1 bacteriocin immunity protein -
  ACGHT2_RS09990 (K460107A9_18780) - 1911188..1911487 (-) 300 WP_195990865.1 DUF3884 family protein -
  ACGHT2_RS09995 (K460107A9_18790) comC/comC1 1911778..1911918 (+) 141 WP_195990863.1 competence protein Regulator
  ACGHT2_RS10000 (K460107A9_18800) - 1911940..1913247 (-) 1308 WP_270619824.1 sensor histidine kinase -
  ACGHT2_RS10005 (K460107A9_18810) comE/comE1 1913255..1913986 (-) 732 WP_058692509.1 response regulator transcription factor Regulator
  ACGHT2_RS10010 (K460107A9_18820) - 1914003..1914287 (-) 285 WP_003066573.1 LytTR family DNA-binding domain-containing protein -
  ACGHT2_RS10015 (K460107A9_18830) - 1914530..1914730 (-) 201 WP_058692510.1 hypothetical protein -
  ACGHT2_RS10020 (K460107A9_18840) - 1914985..1915998 (-) 1014 WP_003066577.1 hypothetical protein -
  ACGHT2_RS10025 (K460107A9_18850) - 1916170..1916466 (-) 297 WP_003066579.1 bacteriocin immunity protein -
  ACGHT2_RS10030 (K460107A9_18860) - 1916466..1916684 (-) 219 WP_003066580.1 Blp family class II bacteriocin -
  ACGHT2_RS10035 (K460107A9_18880) - 1917260..1917490 (-) 231 WP_058692512.1 bacteriocin class II family protein -
  ACGHT2_RS10040 - 1917683..1917802 (-) 120 WP_253066439.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  ACGHT2_RS10045 - 1917799..1918146 (-) 348 WP_231729919.1 CPBP family intramembrane glutamic endopeptidase -
  ACGHT2_RS10050 (K460107A9_18900) - 1918176..1918355 (-) 180 WP_003066584.1 hypothetical protein -
  ACGHT2_RS10055 (K460107A9_18910) - 1918525..1918836 (-) 312 WP_003066586.1 hypothetical protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28430.52 Da        Isoelectric Point: 5.2357

>NTDB_id=109633 ACGHT2_RS10005 WP_058692509.1 1913255..1913986(-) (comE/comE1) [Streptococcus pasteurianus strain k46-0107-A9]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREQ
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTRNERVEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDKAIRSVYFETGDSCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=109633 ACGHT2_RS10005 WP_058692509.1 1913255..1913986(-) (comE/comE1) [Streptococcus pasteurianus strain k46-0107-A9]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCCGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCCATTCGTGAACAA
GATGCAACGGCTATCATTGTTTTTGTAACAACCCATTCAGAATTTATGCTGCTGACTTACCAAGCGTTAGTAGGGGCGAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAAAATTCCTTTTTGTTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGACATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGTGTGATTTTGCATACGAGAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGATAAACGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCGATACGAAGTGTTTATTTCGAAACTGGGGACTCTTGCTTAGTTTCGAGGGATAAAATAAAACCTCTATTGAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-238)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

71.193

100

0.712
  comE/blpR Streptococcus mutans UA159

48.954

98.354

0.481
  comE/comE2 Streptococcus equinus JB1

45.868

99.588

0.457

Multiple sequence alignment