Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACMVYO_RS03370 Genome accession   NZ_CP180296
Coordinates   672052..672681 (-) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis strain YSMAS1_1_D4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 667052..677681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMVYO_RS03340 (ACMVYO_03340) - 667748..668281 (-) 534 WP_017175224.1 acyl-CoA thioesterase -
  ACMVYO_RS03345 (ACMVYO_03345) - 668314..669561 (-) 1248 WP_017175225.1 aminopeptidase -
  ACMVYO_RS03350 (ACMVYO_03350) - 669573..669779 (-) 207 WP_002450082.1 DUF1128 domain-containing protein -
  ACMVYO_RS03355 (ACMVYO_03355) - 669921..670385 (+) 465 WP_017175226.1 low molecular weight protein-tyrosine-phosphatase -
  ACMVYO_RS03360 (ACMVYO_03360) - 670391..670672 (+) 282 WP_049434620.1 hypothetical protein -
  ACMVYO_RS03365 (ACMVYO_03365) - 670764..671972 (+) 1209 WP_049415638.1 YihY/virulence factor BrkB family protein -
  ACMVYO_RS03370 (ACMVYO_03370) vraR 672052..672681 (-) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  ACMVYO_RS03375 (ACMVYO_03375) vraS 672683..673717 (-) 1035 WP_017175228.1 sensor histidine kinase Regulator
  ACMVYO_RS03380 (ACMVYO_03380) liaF 673714..674415 (-) 702 WP_048761633.1 cell wall-active antibiotics response protein LiaF -
  ACMVYO_RS03385 (ACMVYO_03385) - 674436..674822 (-) 387 WP_019835590.1 hypothetical protein -
  ACMVYO_RS03390 (ACMVYO_03390) - 675153..675245 (+) 93 Protein_634 hypothetical protein -
  ACMVYO_RS03395 (ACMVYO_03395) map 675498..676250 (-) 753 WP_049382583.1 type I methionyl aminopeptidase -
  ACMVYO_RS03400 (ACMVYO_03400) - 676424..677413 (+) 990 WP_049434617.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=1095118 ACMVYO_RS03370 WP_002450048.1 672052..672681(-) (vraR) [Staphylococcus hominis strain YSMAS1_1_D4]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1095118 ACMVYO_RS03370 WP_002450048.1 672052..672681(-) (vraR) [Staphylococcus hominis strain YSMAS1_1_D4]
ATGACGATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGAGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCATATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGAGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCCAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTCGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment