Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   ACLCDX_RS11595 Genome accession   NZ_CP180263
Coordinates   2287772..2288065 (-) Length   97 a.a.
NCBI ID   WP_024422977.1    Uniprot ID   A0A0M2EIN6
Organism   Bacillus safensis strain BS22LVI     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2282772..2293065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLCDX_RS11550 (ACLCDX_11550) sinR 2282934..2283269 (+) 336 WP_024422969.1 transcriptional regulator SinR Regulator
  ACLCDX_RS11555 (ACLCDX_11555) tasA 2283337..2284137 (-) 801 WP_024422970.1 biofilm matrix protein TasA -
  ACLCDX_RS11560 (ACLCDX_11560) sipW 2284192..2284764 (-) 573 WP_024422971.1 signal peptidase I SipW -
  ACLCDX_RS11565 (ACLCDX_11565) tapA 2284817..2285344 (-) 528 WP_098677430.1 amyloid fiber anchoring/assembly protein TapA -
  ACLCDX_RS11570 (ACLCDX_11570) - 2285644..2285922 (+) 279 WP_171464609.1 DUF3889 domain-containing protein -
  ACLCDX_RS11575 (ACLCDX_11575) - 2285956..2286150 (-) 195 WP_056767455.1 YqzE family protein -
  ACLCDX_RS11580 (ACLCDX_11580) - 2286217..2286600 (-) 384 WP_197172668.1 competence type IV pilus minor pilin ComGG -
  ACLCDX_RS11585 (ACLCDX_11585) comGF 2286597..2287349 (-) 753 WP_415315994.1 competence type IV pilus minor pilin ComGF -
  ACLCDX_RS11590 (ACLCDX_11590) comGD 2287333..2287779 (-) 447 WP_197172667.1 competence type IV pilus minor pilin ComGD -
  ACLCDX_RS11595 (ACLCDX_11595) comGC 2287772..2288065 (-) 294 WP_024422977.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLCDX_RS11600 (ACLCDX_11600) comGB 2288082..2289122 (-) 1041 WP_197172666.1 competence type IV pilus assembly protein ComGB -
  ACLCDX_RS11605 (ACLCDX_11605) comGA 2289103..2290173 (-) 1071 WP_025092972.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLCDX_RS11610 (ACLCDX_11610) - 2290351..2291226 (-) 876 WP_024422979.1 STAS domain-containing protein -
  ACLCDX_RS11620 (ACLCDX_11620) - 2291450..2291830 (-) 381 WP_007501232.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
  ACLCDX_RS11625 (ACLCDX_11625) - 2292043..2292285 (+) 243 WP_003217440.1 DUF2626 domain-containing protein -
  ACLCDX_RS11630 (ACLCDX_11630) - 2292333..2292971 (-) 639 WP_024422981.1 MBL fold metallo-hydrolase -

Sequence


Protein


Download         Length: 97 a.a.        Molecular weight: 10686.62 Da        Isoelectric Point: 7.3218

>NTDB_id=1094976 ACLCDX_RS11595 WP_024422977.1 2287772..2288065(-) (comGC) [Bacillus safensis strain BS22LVI]
MNDKGFTLLEMLIVMLVISILLLITIPNITRHHQAIQAKGCEGLKSMVSTQVMAYELEHDGKTPSLAELEKEGYVKKGLT
CPNGKAIVIQNGNVKHE

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1094976 ACLCDX_RS11595 WP_024422977.1 2287772..2288065(-) (comGC) [Bacillus safensis strain BS22LVI]
ATGAATGATAAAGGATTTACCCTGTTAGAAATGTTAATAGTCATGCTCGTAATATCCATTCTTTTACTCATTACCATACC
GAATATCACACGTCATCACCAAGCGATTCAGGCAAAGGGCTGTGAAGGGCTTAAATCAATGGTCAGCACACAAGTGATGG
CATATGAATTGGAGCATGATGGGAAGACGCCATCTTTAGCTGAATTAGAAAAAGAAGGTTATGTCAAAAAGGGATTAACT
TGTCCTAATGGAAAAGCGATTGTCATTCAAAACGGCAACGTGAAGCATGAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0M2EIN6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Bacillus subtilis subsp. subtilis str. 168

67.01

100

0.67

  comGC Staphylococcus aureus MW2

42.222

92.784

0.392

  comGC Staphylococcus aureus N315

42.222

92.784

0.392


Multiple sequence alignment