Detailed information NTG0109057

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ACAM21_RS08745
• Genome accession: NZ_AP031395
• Coordinates: 1687787..1688446 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565027.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1682787..1693446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS08720 (SPNE16P29_17230)	-	1683092..1683409 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
ACAM21_RS08725 (SPNE16P29_17240)	-	1683424..1684320 (-)	897	WP_000825667.1	PEP phosphonomutase	-
ACAM21_RS08730 (SPNE16P29_17250)	-	1684323..1685585 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
ACAM21_RS08735 (SPNE16P29_17260)	-	1685865..1687043 (+)	1179	WP_000175880.1	ROK family transcriptional regulator	-
ACAM21_RS08740 (SPNE16P29_17270)	-	1687271..1687717 (-)	447	WP_000155408.1	GNAT family N-acetyltransferase	-
ACAM21_RS08745 (SPNE16P29_17280)	cclA/cilC	1687787..1688446 (+)	660	WP_000565027.1	A24 family peptidase	Machinery gene
ACAM21_RS08750 (SPNE16P29_17290)	trpA	1688418..1689194 (-)	777	WP_219599503.1	tryptophan synthase subunit alpha	-
ACAM21_RS08755 (SPNE16P29_17300)	trpB	1689187..1690410 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
ACAM21_RS08760 (SPNE16P29_17310)	-	1690388..1690987 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
ACAM21_RS08765 (SPNE16P29_17320)	trpC	1690974..1691741 (-)	768	WP_000076545.1	indole-3-glycerol phosphate synthase TrpC	-
ACAM21_RS08770 (SPNE16P29_17330)	trpD	1691738..1692742 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
ACAM21_RS08775 (SPNE16P29_17340)	-	1692753..1693319 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24855.00 Da
• Isoelectric Point: 7.2564

>NTDB_id=109057 ACAM21_RS08745 WP_000565027.1 1687787..1688446(+) (cclA/cilC) [Streptococcus pneumoniae strain 16P29]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=109057 ACAM21_RS08745 WP_000565027.1 1687787..1688446(+) (cclA/cilC) [Streptococcus pneumoniae strain 16P29]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae D39	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae R6	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.845	100	0.858