Detailed information NTG1089301

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ACLSIV_RS07850
• Genome accession: NZ_CP178385
• Coordinates: 1586372..1588624 (-)
• Length: 750 a.a.
• NCBI ID: WP_254066781.1
• Uniprot ID: -
• Organism: Lactococcus raffinolactis strain GCULR
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1581372..1593624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLSIV_RS07820 (ACLSIV_07820)	atpA	1581629..1583134 (-)	1506	WP_061773979.1	F0F1 ATP synthase subunit alpha	-
ACLSIV_RS07825 (ACLSIV_07825)	-	1583275..1583802 (-)	528	WP_061773978.1	F0F1 ATP synthase subunit delta	-
ACLSIV_RS07830 (ACLSIV_07830)	atpF	1583805..1584314 (-)	510	WP_061773977.1	F0F1 ATP synthase subunit B	-
ACLSIV_RS07835 (ACLSIV_07835)	atpB	1584327..1585037 (-)	711	WP_096039368.1	F0F1 ATP synthase subunit A	-
ACLSIV_RS07840 (ACLSIV_07840)	-	1585143..1585343 (-)	201	WP_003140734.1	F0F1 ATP synthase subunit C	-
ACLSIV_RS07845 (ACLSIV_07845)	-	1585499..1586293 (-)	795	WP_412921243.1	alpha/beta hydrolase	-
ACLSIV_RS07850 (ACLSIV_07850)	comEC	1586372..1588624 (-)	2253	WP_254066781.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACLSIV_RS07855 (ACLSIV_07855)	-	1588590..1589243 (-)	654	WP_254066780.1	helix-hairpin-helix domain-containing protein	-
ACLSIV_RS07860 (ACLSIV_07860)	-	1589301..1590521 (-)	1221	WP_167838872.1	ABC transporter permease	-
ACLSIV_RS07865 (ACLSIV_07865)	-	1590514..1591407 (-)	894	WP_061773972.1	ABC transporter ATP-binding protein	-
ACLSIV_RS07870 (ACLSIV_07870)	-	1591582..1592016 (-)	435	WP_061773971.1	hypothetical protein	-
ACLSIV_RS07875 (ACLSIV_07875)	-	1592072..1592266 (-)	195	WP_061773970.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 85639.71 Da
• Isoelectric Point: 10.1525

>NTDB_id=1089301 ACLSIV_RS07850 WP_254066781.1 1586372..1588624(-) (comEC) [Lactococcus raffinolactis strain GCULR]
MKNLKKALRWINLPSIFIAYFCVLIYYTVFCFSYLLLGYLIISLLILIWQNGIRTCLKLSMILIGFATICLALQDREAKD
FAREMTVTRISPILDTIQVDGDQVSFRGKSGKQTYQVYYRVTTEQEQRYFKQLAQPVVLSISGQLEKASQQRNFNGFDYQ
HHLKTQNIYRVLTIEQVTGVTRKQTLTLALLRRKAILFSEQHFPRPMSAYMTGLLFGHLGKDFEDMSSIYTSLGIMHLFA
LSGMQVSFFIDFLRKGMLRLGFRRDVVDWFQIPFSVFYAGLTGFSISVNRSLVQKILANFGIKALDNFSLTLLLLFITAP
KFLLTTGGTLSLLFAFVISIFGDRFENLPKYRKLLAESLTLSLCVLPLLILYFHTFQPVSIILTFVFSFLFDILFLPGLS
VIFLLAMVTGFTLTQVNLIFQWLEDLIKLTDSWWHYPLVLGKPTALVFLVTLVVTGFLIDHWRNRKVSARLAIILMGLFF
ITKNPPTPSMTMVDVGQGDSIFLQDKFNRRNILIDTGGRIELGKKKKWQERKIAAPAEKTLIPYLKSRGVGQIDTLVLTH
THEDHMGDLLAVIDQIKVKNIIVSQGSLNNAQFVKLLKQTRAKVQVAKVGQRLKIFDSYLEVLYPLTSGDGKNNDSIVLY
GKLYGTKFLLTGDLEETGERELLTRYPNLSVDVLKVGHHGSKTSSSESFIEAIRPKVGLISCGFDNRYGHPNMETLTTFQ
KYEVQTFRTDYHGAIKFKKNSKFWHISTVK

Nucleotide

• Length: 2253 bp

>NTDB_id=1089301 ACLSIV_RS07850 WP_254066781.1 1586372..1588624(-) (comEC) [Lactococcus raffinolactis strain GCULR]
TTGAAAAACTTAAAGAAAGCATTACGGTGGATTAATCTACCATCGATTTTCATCGCCTATTTTTGTGTGCTGATCTACTA
TACCGTCTTTTGTTTCTCCTATTTACTTTTAGGTTATCTCATCATTTCTTTGCTAATCTTGATCTGGCAAAATGGCATCA
GAACTTGTTTAAAGCTCAGCATGATCTTAATTGGGTTTGCAACCATTTGTCTAGCGCTACAAGATCGTGAAGCTAAAGAT
TTTGCGCGTGAGATGACAGTGACACGGATCAGCCCCATACTGGATACGATTCAGGTGGATGGTGACCAGGTCTCTTTTCG
TGGGAAATCGGGCAAACAAACCTATCAAGTCTATTATAGGGTCACGACGGAACAAGAGCAGCGCTACTTTAAGCAATTAG
CACAACCAGTCGTCCTATCCATTTCAGGTCAACTAGAAAAAGCGAGTCAACAAAGAAATTTCAATGGCTTTGATTATCAA
CACCATCTCAAGACACAAAATATCTATCGAGTTTTGACGATTGAACAGGTGACAGGGGTGACAAGAAAACAAACCTTAAC
CTTAGCGCTCTTACGACGAAAAGCTATTTTGTTTAGTGAGCAACACTTTCCGCGACCTATGTCAGCCTACATGACCGGTT
TACTTTTTGGGCATCTCGGTAAAGATTTTGAAGATATGAGCAGTATCTATACCAGCTTAGGCATCATGCACCTCTTTGCG
CTATCAGGCATGCAAGTGTCATTTTTTATCGACTTTTTAAGAAAGGGTATGCTCAGACTAGGGTTCAGGAGAGATGTTGT
CGATTGGTTTCAAATCCCTTTTTCTGTTTTTTATGCTGGTCTTACAGGATTTTCCATATCTGTCAACAGATCCTTGGTCC
AGAAAATCCTAGCTAATTTTGGAATTAAGGCGCTTGACAATTTCAGTCTCACGTTGTTGCTTCTATTTATCACGGCGCCA
AAATTCCTTTTAACCACAGGCGGCACCTTGTCTTTACTTTTTGCCTTCGTCATTTCAATCTTTGGTGATCGCTTTGAGAA
CCTCCCAAAATATCGTAAACTACTAGCAGAAAGTTTAACCCTTTCTCTATGCGTTTTACCGCTCCTCATCCTTTATTTTC
ACACCTTCCAACCAGTGTCGATCATCTTGACTTTTGTCTTCAGCTTTCTTTTTGATATTCTCTTCCTACCAGGTCTATCC
GTCATTTTCTTGCTAGCAATGGTAACAGGCTTCACGCTAACACAAGTCAATCTCATTTTTCAGTGGCTTGAAGACCTTAT
CAAATTGACAGATAGCTGGTGGCATTATCCGTTAGTACTTGGTAAACCAACAGCCTTGGTCTTTCTGGTGACGCTAGTTG
TGACAGGTTTTTTAATTGACCACTGGCGAAATCGAAAAGTTAGTGCTAGGCTAGCAATCATCTTGATGGGCTTATTCTTC
ATAACTAAAAATCCACCGACCCCTTCGATGACCATGGTGGACGTTGGTCAGGGGGATAGTATTTTCTTGCAAGATAAGTT
TAATCGACGCAATATTTTAATCGATACAGGTGGCAGGATTGAATTAGGTAAGAAGAAAAAGTGGCAGGAGCGTAAAATAG
CAGCGCCAGCTGAAAAGACTTTAATTCCTTATTTGAAAAGTCGGGGTGTGGGTCAGATTGATACTTTGGTTCTAACCCAT
ACTCACGAGGACCATATGGGTGACCTACTCGCTGTCATCGACCAAATTAAGGTTAAAAATATCATCGTAAGTCAAGGCAG
TCTTAATAATGCCCAATTTGTCAAACTCTTAAAGCAAACCCGAGCTAAGGTTCAAGTGGCCAAGGTCGGTCAACGGCTAA
AGATTTTTGACAGCTATTTGGAAGTTCTGTATCCATTGACCTCAGGAGACGGTAAAAATAATGACTCGATCGTCTTGTAT
GGTAAGCTCTATGGGACAAAATTTTTGTTAACAGGTGATTTGGAGGAGACAGGCGAGCGAGAGTTGTTGACACGTTATCC
CAATCTCTCAGTTGATGTTTTAAAAGTAGGGCATCATGGCTCAAAAACGTCATCTTCTGAGTCTTTTATTGAAGCGATTC
GACCAAAAGTCGGATTGATTTCTTGTGGTTTTGATAATCGGTACGGTCATCCAAATATGGAAACTCTCACAACCTTCCAG
AAATATGAGGTTCAAACTTTTCGAACAGATTATCATGGTGCTATAAAATTTAAGAAAAACAGTAAATTTTGGCACATCTC
GACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-703)

• Domain of unknown function (DUF4131) (DUF4131) (34-178)

• Competence protein (Competence) (214-463)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	51.822	98.8	0.512
comEC/celB	Streptococcus mitis NCTC 12261	46.817	100	0.471
comEC/celB	Streptococcus mitis SK321	46.235	100	0.467
comEC/celB	Streptococcus pneumoniae TIGR4	45.358	100	0.456
comEC/celB	Streptococcus pneumoniae Rx1	43.857	100	0.443
comEC/celB	Streptococcus pneumoniae D39	43.857	100	0.443
comEC/celB	Streptococcus pneumoniae R6	43.857	100	0.443