Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   ACJWMD_RS09550 Genome accession   NZ_CP177182
Coordinates   2005056..2006012 (-) Length   318 a.a.
NCBI ID   WP_002887012.1    Uniprot ID   A0A1F2HRB9
Organism   Streptococcus salivarius strain MRD6060     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2000056..2011012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS09520 proC 2000598..2001368 (+) 771 WP_002887008.1 pyrroline-5-carboxylate reductase -
  ACJWMD_RS09525 - 2001395..2002057 (-) 663 WP_002887009.1 CPBP family intramembrane glutamic endopeptidase -
  ACJWMD_RS09530 - 2002170..2002616 (-) 447 WP_037605837.1 hypothetical protein -
  ACJWMD_RS09535 - 2002690..2003346 (-) 657 WP_002887011.1 CPBP family intramembrane glutamic endopeptidase -
  ACJWMD_RS09540 - 2003358..2003555 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  ACJWMD_RS09545 - 2003806..2004999 (-) 1194 WP_002885831.1 acetate kinase -
  ACJWMD_RS09550 comYH 2005056..2006012 (-) 957 WP_002887012.1 class I SAM-dependent methyltransferase Machinery gene
  ACJWMD_RS09555 comGG 2006057..2006374 (-) 318 WP_002887013.1 competence type IV pilus minor pilin ComGG -
  ACJWMD_RS09560 comYF 2006352..2006789 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACJWMD_RS09565 comGE 2006776..2007006 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  ACJWMD_RS09570 comYD 2007038..2007466 (-) 429 WP_254593949.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACJWMD_RS09575 comYC 2007426..2007740 (-) 315 WP_170314557.1 competence type IV pilus major pilin ComGC Machinery gene
  ACJWMD_RS09580 comYB 2007749..2008849 (-) 1101 WP_139053029.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACJWMD_RS09585 comGA/cglA/cilD 2008731..2009672 (-) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene
  ACJWMD_RS09590 - 2009751..2010113 (-) 363 WP_002887019.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35760.65 Da        Isoelectric Point: 4.3805

>NTDB_id=1086036 ACJWMD_RS09550 WP_002887012.1 2005056..2006012(-) (comYH) [Streptococcus salivarius strain MRD6060]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDVLEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=1086036 ACJWMD_RS09550 WP_002887012.1 2005056..2006012(-) (comYH) [Streptococcus salivarius strain MRD6060]
ATGAATTTTGAAGCAATTGAGACAGCCTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCGCTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCCCTTAATCTAAGCAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAGCTAGGGCAATTG
GAAGCCTTACAAGCCAATCACCAATTTACACCTGATGCTATTGGATTTATCATTCTTTACCTACTTGAAGGTTTGACCAA
GGACGACCAATTAGATGTTTTGGAGATTGGTTCGGGGACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCGAGT
GCAGTTTACATTCAAGAAGATGCTGTTCGACCACATATTCTCAAAGAGAGTGATGTTATTATTAGTGACCTACCTGTTGG
TTACTACCCTAATGATGAAATTGCGAGTCGTTTCAAGGTTGCAGCAACCGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGATTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTTAAAAAACAAACTGAAAATGCTCCTGAGACCTTCGTTTATCCACTTAGTG
ATTTGCAAAACCCAGAGGTCCTCAAAGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1F2HRB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.476

99.057

0.698
  comYH Streptococcus mutans UA140

70.476

99.057

0.698

Multiple sequence alignment