Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACJWMD_RS01570 Genome accession   NZ_CP177182
Coordinates   287907..288596 (+) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 282907..293596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS01545 - 283209..284039 (+) 831 WP_002886584.1 energy-coupling factor transporter transmembrane component T family protein -
  ACJWMD_RS01550 - 284129..284800 (-) 672 WP_002886585.1 potassium channel family protein -
  ACJWMD_RS01555 - 284840..286155 (-) 1316 Protein_256 TrkH family potassium uptake protein -
  ACJWMD_RS01560 rsmG 286203..286916 (-) 714 WP_002886587.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ACJWMD_RS01565 - 287215..287751 (+) 537 WP_002886588.1 DUF177 domain-containing protein -
  ACJWMD_RS01570 covR 287907..288596 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  ACJWMD_RS01575 covS 288593..290122 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  ACJWMD_RS01580 nrdR 290244..290723 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  ACJWMD_RS01585 - 290720..291895 (+) 1176 WP_002886594.1 DnaD domain protein -
  ACJWMD_RS01590 dnaI 291899..292801 (+) 903 WP_002886595.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=1085990 ACJWMD_RS01570 WP_002886589.1 287907..288596(+) (covR) [Streptococcus salivarius strain MRD6060]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1085990 ACJWMD_RS01570 WP_002886589.1 287907..288596(+) (covR) [Streptococcus salivarius strain MRD6060]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTATTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment