Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACKWPP_RS05185 Genome accession   NZ_CP176418
Coordinates   981491..982870 (+) Length   459 a.a.
NCBI ID   WP_024401460.1    Uniprot ID   -
Organism   Streptococcus suis strain KKAHC02     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 976491..987870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS05155 (ACKWPP_05155) pstA 976917..977804 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  ACKWPP_RS05160 (ACKWPP_05160) pstB 977829..978632 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  ACKWPP_RS05165 (ACKWPP_05165) pstB 978644..979402 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  ACKWPP_RS05170 (ACKWPP_05170) phoU 979431..980087 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  ACKWPP_RS05175 (ACKWPP_05175) - 980253..980633 (+) 381 WP_024401461.1 hypothetical protein -
  ACKWPP_RS05180 (ACKWPP_05180) ciaR 980827..981498 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  ACKWPP_RS05185 (ACKWPP_05185) ciaH 981491..982870 (+) 1380 WP_024401460.1 sensor histidine kinase Regulator
  ACKWPP_RS05190 (ACKWPP_05190) - 982971..984200 (+) 1230 WP_024401459.1 transglutaminase domain-containing protein -
  ACKWPP_RS05195 (ACKWPP_05195) rpsT 984464..984712 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  ACKWPP_RS05200 (ACKWPP_05200) coaA 984771..985691 (-) 921 WP_002935283.1 type I pantothenate kinase -
  ACKWPP_RS05205 (ACKWPP_05205) - 985860..986990 (+) 1131 WP_024400816.1 ISAs1 family transposase -
  ACKWPP_RS05210 (ACKWPP_05210) - 987122..987712 (+) 591 WP_409374324.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51862.42 Da        Isoelectric Point: 5.8702

>NTDB_id=1080062 ACKWPP_RS05185 WP_024401460.1 981491..982870(+) (ciaH) [Streptococcus suis strain KKAHC02]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKETTVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=1080062 ACKWPP_RS05185 WP_024401460.1 981491..982870(+) (ciaH) [Streptococcus suis strain KKAHC02]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAACAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTTGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGTTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTACGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGTATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTGACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49

Multiple sequence alignment