Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACJSOD_RS02195 Genome accession   NZ_CP174508
Coordinates   456620..457957 (+) Length   445 a.a.
NCBI ID   WP_104052949.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain KS1-2     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 451620..462957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJSOD_RS02170 (ACJSOD_02170) pgeF 451763..452491 (-) 729 WP_003112833.1 peptidoglycan editing factor PgeF -
  ACJSOD_RS02175 (ACJSOD_02175) rluD 452488..453450 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  ACJSOD_RS02180 (ACJSOD_02180) - 453596..454621 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  ACJSOD_RS02185 (ACJSOD_02185) - 454778..455023 (+) 246 WP_003102591.1 PP0621 family protein -
  ACJSOD_RS02190 (ACJSOD_02190) pilS 455013..456605 (+) 1593 WP_003123394.1 two-component system sensor histidine kinase PilS Regulator
  ACJSOD_RS02195 (ACJSOD_02195) pilR 456620..457957 (+) 1338 WP_104052949.1 two-component system response regulator PilR Regulator
  ACJSOD_RS02200 (ACJSOD_02200) thiO 458003..459097 (-) 1095 WP_212648728.1 glycine oxidase ThiO -
  ACJSOD_RS02205 (ACJSOD_02205) - 459232..459741 (+) 510 WP_003102595.1 Tfp pilus assembly protein FimT/FimU -
  ACJSOD_RS02210 (ACJSOD_02210) - 459847..460353 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  ACJSOD_RS02215 (ACJSOD_02215) pilV 460344..460901 (+) 558 WP_408014393.1 type 4a pilus minor pilin PilV Machinery gene
  ACJSOD_RS02220 (ACJSOD_02220) pilW 460898..461722 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  ACJSOD_RS02225 (ACJSOD_02225) pilX 461719..462306 (+) 588 WP_015648054.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49727.02 Da        Isoelectric Point: 5.8654

>NTDB_id=1077489 ACJSOD_RS02195 WP_104052949.1 456620..457957(+) (pilR) [Pseudomonas aeruginosa strain KS1-2]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEASVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1077489 ACJSOD_RS02195 WP_104052949.1 456620..457957(+) (pilR) [Pseudomonas aeruginosa strain KS1-2]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGTCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.274

100

0.389

Multiple sequence alignment