Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   ACAM22_RS09810 Genome accession   NZ_AP028929
Coordinates   2088030..2088266 (-) Length   78 a.a.
NCBI ID   WP_000940045.1    Uniprot ID   E1LR49
Organism   Streptococcus sp. SN-1     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2089056..2089556 2088030..2088266 flank 790


Gene organization within MGE regions


Location: 2088030..2089556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS09810 (MASAN616_18870) comW 2088030..2088266 (-) 237 WP_000940045.1 sigma(X)-activator ComW Regulator

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9830.29 Da        Isoelectric Point: 6.2034

>NTDB_id=107367 ACAM22_RS09810 WP_000940045.1 2088030..2088266(-) (comW) [Streptococcus sp. SN-1]
MLQNIYDQMTDFYDSIEEEYATFFGNSWDWEHFHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKMIMKQGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=107367 ACAM22_RS09810 WP_000940045.1 2088030..2088266(-) (comW) [Streptococcus sp. SN-1]
ATGCTACAAAATATTTATGATCAGATGACTGATTTCTATGACAGTATCGAAGAAGAGTATGCTACTTTCTTTGGTAATAG
TTGGGACTGGGAACATTTTCATTTTAAATTTTTGATTTATTATTTAGTTAGATATGGTATTGGGTGTCGTAGGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAGATGATAATGAAACAAGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E1LR49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

79.487

100

0.795
  comW Streptococcus pneumoniae D39

79.487

100

0.795
  comW Streptococcus pneumoniae R6

79.487

100

0.795
  comW Streptococcus pneumoniae TIGR4

79.487

100

0.795
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756

Multiple sequence alignment