Detailed information NTG0107205

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: AAA995_RS08515
• Genome accession: NZ_AP028877
• Coordinates: 1670838..1671497 (+)
• Length: 219 a.a.
• NCBI ID: WP_000564991.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21P20
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1665838..1676497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS08490 (SP21P20_16900)	-	1666143..1666460 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
AAA995_RS08495 (SP21P20_16910)	-	1666475..1667371 (-)	897	WP_000825665.1	PEP phosphonomutase	-
AAA995_RS08500 (SP21P20_16920)	-	1667368..1668636 (-)	1269	WP_000413337.1	PTS sugar transporter subunit IIC	-
AAA995_RS08505 (SP21P20_16930)	-	1668916..1670094 (+)	1179	WP_000175879.1	ROK family transcriptional regulator	-
AAA995_RS08510 (SP21P20_16940)	-	1670322..1670768 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
AAA995_RS08515 (SP21P20_16950)	cclA/cilC	1670838..1671497 (+)	660	WP_000564991.1	A24 family peptidase	Machinery gene
AAA995_RS08520 (SP21P20_16960)	-	1671549..1672700 (-)	1152	WP_000481750.1	XRE family transcriptional regulator	-
AAA995_RS08525 (SP21P20_16970)	-	1672715..1673446 (-)	732	WP_000934018.1	hypothetical protein	-
AAA995_RS08530	-	1673675..1673776 (+)	102	Protein_1688	prepilin peptidase	-
AAA995_RS08535 (SP21P20_16980)	trpA	1673748..1674524 (-)	777	WP_001127044.1	tryptophan synthase subunit alpha	-
AAA995_RS08540 (SP21P20_16990)	trpB	1674517..1675740 (-)	1224	WP_000331294.1	tryptophan synthase subunit beta	-
AAA995_RS08545 (SP21P20_17000)	-	1675718..1676317 (-)	600	WP_000169912.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24880.03 Da
• Isoelectric Point: 7.9671

>NTDB_id=107205 AAA995_RS08515 WP_000564991.1 1670838..1671497(+) (cclA/cilC) [Streptococcus pneumoniae strain 21P20]
MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=107205 AAA995_RS08515 WP_000564991.1 1670838..1671497(+) (cclA/cilC) [Streptococcus pneumoniae strain 21P20]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGAA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae D39	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae R6	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.388	100	0.854