Detailed information NTG0107189

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AAA995_RS04670
• Genome accession: NZ_AP028877
• Coordinates: 906409..907362 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 21P20
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 901409..912362

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS04645	rpmG	902152..902301 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
AAA995_RS04650 (SP21P20_09120)	secG	902341..902574 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
AAA995_RS04655 (SP21P20_09130)	rnr	902676..905030 (+)	2355	WP_088778490.1	ribonuclease R	-
AAA995_RS04660 (SP21P20_09140)	smpB	904993..905460 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
AAA995_RS04665 (SP21P20_09150)	tehB	905476..906336 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
AAA995_RS04670 (SP21P20_09160)	coiA	906409..907362 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
AAA995_RS04675 (SP21P20_09170)	pepF	907381..909183 (+)	1803	WP_088778489.1	oligoendopeptidase F	Regulator
AAA995_RS04680 (SP21P20_09180)	-	909185..909898 (+)	714	WP_001810028.1	O-methyltransferase	-
AAA995_RS04685 (SP21P20_09190)	prsA	909965..910906 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
AAA995_RS04690 (SP21P20_09200)	-	911025..911366 (-)	342	Protein_925	IS3 family transposase	-
AAA995_RS04695	-	911778..911873 (+)	96	Protein_926	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=107189 AAA995_RS04670 WP_000495909.1 906409..907362(+) (coiA) [Streptococcus pneumoniae strain 21P20]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=107189 AAA995_RS04670 WP_000495909.1 906409..907362(+) (coiA) [Streptococcus pneumoniae strain 21P20]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435