Detailed information NTG1071075

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: ACIRXM_RS05615
• Genome accession: NZ_CP173234
• Coordinates: 1089016..1090338 (+)
• Length: 440 a.a.
• NCBI ID: WP_035688106.1
• Uniprot ID: -
• Organism: Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1079616..1089007	1089016..1090338	flank	9

Gene organization within MGE regions

Location: 1079616..1090338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIRXM_RS05570 (ACIRXM_05575)	-	1079616..1079999 (+)	384	WP_035688085.1	endonuclease domain-containing protein	-
ACIRXM_RS05575 (ACIRXM_05580)	-	1080198..1080803 (+)	606	WP_410687685.1	hypothetical protein	-
ACIRXM_RS05580 (ACIRXM_05585)	glyS	1080829..1082892 (+)	2064	WP_410687687.1	glycine--tRNA ligase subunit beta	-
ACIRXM_RS05585 (ACIRXM_05590)	-	1083064..1084020 (+)	957	WP_410687689.1	alpha-2,3-sialyltransferase	-
ACIRXM_RS05590 (ACIRXM_05595)	-	1084117..1086666 (-)	2550	WP_410687690.1	penicillin-binding protein 1A	-
ACIRXM_RS05595 (ACIRXM_05600)	-	1086825..1087592 (+)	768	WP_264245250.1	hypothetical protein	-
ACIRXM_RS05600 (ACIRXM_05605)	-	1087622..1088134 (+)	513	WP_017806830.1	PilN domain-containing protein	-
ACIRXM_RS05605 (ACIRXM_05610)	-	1088121..1088648 (+)	528	WP_410683657.1	hypothetical protein	-
ACIRXM_RS05610 (ACIRXM_05615)	-	1088648..1089007 (+)	360	WP_410687692.1	hypothetical protein	-
ACIRXM_RS05615 (ACIRXM_05620)	comE	1089016..1090338 (+)	1323	WP_035688106.1	type IV pilus secretin PilQ	Machinery gene

Sequence

Protein

• Length: 440 a.a.
• Molecular weight: 48606.59 Da
• Isoelectric Point: 6.1204

>NTDB_id=1071075 ACIRXM_RS05615 WP_035688106.1 1089016..1090338(+) (comE) [Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1]
MKLPNIIKNILLFFLILSYPFRQVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTEIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide

• Length: 1323 bp

>NTDB_id=1071075 ACIRXM_RS05615 WP_035688106.1 1089016..1090338(+) (comE) [Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1]
ATGAAGTTACCAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACAGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAGGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATCAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGAAATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGAGTCAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACCACAAATA
AGAAAAGTGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
CCAGAATGCACCTGGAGGACGGGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTTGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (129-192)

• Bacterial type II and III secretion system protein (Secretin) (274-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	65.023	96.818	0.63
comE	Haemophilus influenzae 86-028NP	64.789	96.818	0.627
comE	Glaesserella parasuis strain SC1401	49.883	97.045	0.484
pilQ	Vibrio campbellii strain DS40M4	40	96.591	0.386
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	40.288	94.773	0.382
pilQ	Vibrio cholerae strain A1552	40.288	94.773	0.382