Detailed information    

insolico Bioinformatically predicted

Overview


Name   comE1/comEA   Type   Machinery gene
Locus tag   ACIO07_RS05965 Genome accession   NZ_CP173228
Coordinates   1153536..1153892 (-) Length   118 a.a.
NCBI ID   WP_017805052.1    Uniprot ID   A0A0F5EZA2
Organism   Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1148536..1158892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO07_RS05930 (ACIO07_05935) - 1148668..1149045 (-) 378 WP_017805060.1 hypothetical protein -
  ACIO07_RS05935 (ACIO07_05940) - 1149188..1149790 (+) 603 WP_410683390.1 beta-phosphoglucomutase family hydrolase -
  ACIO07_RS05940 (ACIO07_05945) - 1149791..1150399 (+) 609 WP_410683391.1 sugar O-acetyltransferase -
  ACIO07_RS05945 (ACIO07_05950) - 1150392..1150850 (+) 459 WP_110479107.1 YqaA family protein -
  ACIO07_RS05950 (ACIO07_05955) luxS 1151074..1151580 (+) 507 WP_035685396.1 S-ribosylhomocysteine lyase -
  ACIO07_RS05955 (ACIO07_05960) hemW 1151648..1152802 (-) 1155 WP_046098006.1 radical SAM family heme chaperone HemW -
  ACIO07_RS05960 (ACIO07_05965) rdgB 1152802..1153398 (-) 597 WP_035685390.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
  ACIO07_RS05965 (ACIO07_05970) comE1/comEA 1153536..1153892 (-) 357 WP_017805052.1 ComEA family DNA-binding protein Machinery gene
  ACIO07_RS05970 (ACIO07_05975) - 1154154..1155467 (-) 1314 WP_110479111.1 NCS2 family permease -
  ACIO07_RS05975 (ACIO07_05980) - 1155498..1155638 (+) 141 WP_156127777.1 hypothetical protein -
  ACIO07_RS05980 (ACIO07_05985) galE 1155674..1156690 (+) 1017 WP_410683393.1 UDP-glucose 4-epimerase GalE -
  ACIO07_RS05985 (ACIO07_05990) - 1156757..1158025 (+) 1269 WP_410683394.1 AmpG family muropeptide MFS transporter -

Sequence


Protein


Download         Length: 118 a.a.        Molecular weight: 12840.71 Da        Isoelectric Point: 7.0137

>NTDB_id=1070914 ACIO07_RS05965 WP_017805052.1 1153536..1153892(-) (comE1/comEA) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3]
MKIKTILSSLILAITFIGSVYADETVNPPATTQVTDNKTIDTTFIGEKLNINTASASEIQKALVGIGAKKAEAIVEYREQ
HGKFIAPEQLLEVKGIGKAIFEKNKDRIDLSSFNSNSQ

Nucleotide


Download         Length: 357 bp        

>NTDB_id=1070914 ACIO07_RS05965 WP_017805052.1 1153536..1153892(-) (comE1/comEA) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3]
ATGAAAATTAAAACGATTTTATCTTCTCTCATTTTGGCAATAACATTTATTGGTTCGGTTTATGCTGATGAAACAGTGAA
TCCACCAGCCACGACACAAGTGACGGATAATAAAACTATCGACACCACATTTATTGGCGAAAAGCTCAATATTAATACGG
CAAGTGCAAGTGAAATTCAGAAAGCCTTAGTAGGCATTGGGGCGAAGAAAGCAGAAGCTATCGTGGAATATCGAGAACAA
CACGGTAAATTTATCGCACCAGAACAACTATTAGAAGTAAAGGGGATTGGAAAAGCGATTTTTGAAAAAAATAAAGATCG
CATAGATTTATCTTCATTTAATAGTAATAGCCAATAG

Domains


Predicted by InterproScan.

(47-108)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0F5EZA2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

52.679

94.915

0.5

  comEA/comE1 Glaesserella parasuis strain SC1401

50

89.831

0.449

  comEA Vibrio cholerae C6706

41.441

94.068

0.39

  comEA Vibrio cholerae strain A1552

41.441

94.068

0.39


Multiple sequence alignment