Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACIO07_RS00620 Genome accession   NZ_CP173228
Coordinates   126328..127650 (-) Length   440 a.a.
NCBI ID   WP_410682577.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121328..132650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO07_RS00595 (ACIO07_00595) secM 122872..123183 (-) 312 WP_410682572.1 secA translation cis-regulator SecM -
  ACIO07_RS00600 (ACIO07_00600) - 123289..123594 (+) 306 WP_035688115.1 DciA family protein -
  ACIO07_RS00605 (ACIO07_00605) - 123566..124456 (-) 891 WP_410682574.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ACIO07_RS00610 (ACIO07_00610) aroB 124462..125550 (-) 1089 WP_410682575.1 3-dehydroquinate synthase -
  ACIO07_RS00615 (ACIO07_00615) aroK 125567..126127 (-) 561 WP_272487554.1 shikimate kinase AroK -
  ACIO07_RS00620 (ACIO07_00620) comE 126328..127650 (-) 1323 WP_410682577.1 type IV pilus secretin PilQ Machinery gene
  ACIO07_RS00625 (ACIO07_00625) - 127659..128018 (-) 360 WP_017806828.1 hypothetical protein -
  ACIO07_RS00630 (ACIO07_00630) - 128018..129046 (-) 1029 WP_410682579.1 PilN domain-containing protein -
  ACIO07_RS00635 (ACIO07_00635) - 129073..129840 (-) 768 WP_410682581.1 hypothetical protein -
  ACIO07_RS00640 (ACIO07_00640) - 129999..132548 (+) 2550 WP_410682583.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 48593.63 Da        Isoelectric Point: 6.1197

>NTDB_id=1070898 ACIO07_RS00620 WP_410682577.1 126328..127650(-) (comE) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3]
MKLLNIIKNILLFFLILSYPFRLVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTDIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1070898 ACIO07_RS00620 WP_410682577.1 126328..127650(-) (comE) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-3]
ATGAAGTTACTAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACTGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAAGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATAAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGACATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCTCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGCGTTAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGCCCACGATTATTGACTACGAATA
AGAAAAGCGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
CCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(129-192)

Bacterial type II and III secretion system protein (Secretin)

(274-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

64.651

97.727

0.632
  comE Haemophilus influenzae 86-028NP

64.789

96.818

0.627
  comE Glaesserella parasuis strain SC1401

49.883

97.045

0.484
  pilQ Vibrio campbellii strain DS40M4

40

96.591

0.386
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.288

94.773

0.382
  pilQ Vibrio cholerae strain A1552

40.288

94.773

0.382

Multiple sequence alignment