Detailed information NTG1070814

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACIVIR_RS06565
• Genome accession: NZ_CP173225
• Coordinates: 1260222..1261175 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 262
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1255222..1266175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIVIR_RS06540	rpmG	1255965..1256114 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
ACIVIR_RS06545	secG	1256154..1256387 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
ACIVIR_RS06550	rnr	1256489..1258843 (+)	2355	WP_054387412.1	ribonuclease R	-
ACIVIR_RS06555	smpB	1258806..1259273 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
ACIVIR_RS06560	tehB	1259289..1260149 (+)	861	WP_054387413.1	SAM-dependent methyltransferase TehB	-
ACIVIR_RS06565	coiA	1260222..1261175 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
ACIVIR_RS06570	pepF	1261194..1263005 (+)	1812	WP_114880829.1	oligoendopeptidase F	Regulator
ACIVIR_RS06575	-	1263007..1263720 (+)	714	WP_000230399.1	O-methyltransferase	-
ACIVIR_RS06580	prsA	1263787..1264728 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
ACIVIR_RS06585	-	1264845..1265225 (-)	381	Protein_1256	transposase	-
ACIVIR_RS06590	-	1265638..1265733 (+)	96	Protein_1257	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1070814 ACIVIR_RS06565 WP_000495909.1 1260222..1261175(+) (coiA) [Streptococcus pneumoniae strain 262]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1070814 ACIVIR_RS06565 WP_000495909.1 1260222..1261175(+) (coiA) [Streptococcus pneumoniae strain 262]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435