Detailed information NTG1069529

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACFELJ_RS24765
• Genome accession: NZ_CP172859
• Coordinates: 5291500..5292837 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 238629E_ID006
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5286500..5297837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFELJ_RS24740 (ACFELJ_24740)	pgeF	5286643..5287371 (-)	729	WP_058179501.1	peptidoglycan editing factor PgeF	-
ACFELJ_RS24745 (ACFELJ_24745)	rluD	5287368..5288330 (-)	963	WP_033972915.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACFELJ_RS24750 (ACFELJ_24750)	-	5288476..5289501 (+)	1026	WP_033972916.1	outer membrane protein assembly factor BamD	-
ACFELJ_RS24755 (ACFELJ_24755)	-	5289658..5289903 (+)	246	WP_003102591.1	PP0621 family protein	-
ACFELJ_RS24760 (ACFELJ_24760)	pilS	5289893..5291485 (+)	1593	WP_039028118.1	two-component system sensor histidine kinase PilS	Regulator
ACFELJ_RS24765 (ACFELJ_24765)	pilR	5291500..5292837 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACFELJ_RS24770 (ACFELJ_24770)	thiO	5292883..5293977 (-)	1095	WP_110194839.1	glycine oxidase ThiO	-
ACFELJ_RS24775 (ACFELJ_24775)	-	5294112..5294621 (+)	510	WP_110194330.1	Tfp pilus assembly protein FimT/FimU	-
ACFELJ_RS24780 (ACFELJ_24780)	-	5294727..5295233 (+)	507	WP_003134935.1	Tfp pilus assembly protein FimT/FimU	-
ACFELJ_RS24785 (ACFELJ_24785)	pilV	5295224..5295781 (+)	558	WP_003125211.1	type 4a pilus minor pilin PilV	Machinery gene
ACFELJ_RS24790 (ACFELJ_24790)	pilW	5295778..5296602 (+)	825	WP_400637234.1	type 4a pilus minor pilin PilW	-
ACFELJ_RS24795 (ACFELJ_24795)	pilX	5296599..5297186 (+)	588	WP_033972921.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1069529 ACFELJ_RS24765 WP_003094694.1 5291500..5292837(+) (pilR) [Pseudomonas aeruginosa strain 238629E_ID006]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1069529 ACFELJ_RS24765 WP_003094694.1 5291500..5292837(+) (pilR) [Pseudomonas aeruginosa strain 238629E_ID006]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAGGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCCTGCGCAACCCGGAGGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAATCACCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCATGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGTGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGAGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCAGCCGAAGTCGGCGCCGGGCGCTTCCGCCAAGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGACTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTTCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACGCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384