Detailed information NTG0106919

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: AADG46_RS09850
• Genome accession: NZ_AP028804
• Coordinates: 2179571..2180446 (+)
• Length: 291 a.a.
• NCBI ID: WP_000418753.1
• Uniprot ID: -
• Organism: Vibrio cholerae strain VN152
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2174571..2185446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AADG46_RS09830 (VNVC001_18640)	nadC	2175010..2175900 (+)	891	WP_114743264.1	carboxylating nicotinate-nucleotide diphosphorylase	-
AADG46_RS09835 (VNVC001_18650)	-	2176145..2176549 (+)	405	WP_000649343.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
AADG46_RS09840 (VNVC001_18660)	pilB	2176556..2178244 (+)	1689	WP_148503289.1	type IV-A pilus assembly ATPase PilB	Machinery gene
AADG46_RS09845 (VNVC001_18670)	pilC	2178287..2179513 (+)	1227	WP_000648507.1	type II secretion system F family protein	Machinery gene
AADG46_RS09850 (VNVC001_18680)	pilD	2179571..2180446 (+)	876	WP_000418753.1	A24 family peptidase	Machinery gene
AADG46_RS09855 (VNVC001_18690)	coaE	2180443..2181051 (+)	609	WP_000011551.1	dephospho-CoA kinase	-
AADG46_RS09860 (VNVC001_18700)	zapD	2181083..2181823 (+)	741	WP_000207194.1	cell division protein ZapD	-
AADG46_RS09865 (VNVC001_18710)	yacG	2181981..2182178 (+)	198	WP_000162866.1	DNA gyrase inhibitor YacG	-
AADG46_RS09870 (VNVC001_18720)	parC	2182465..2184750 (-)	2286	WP_172780947.1	DNA topoisomerase IV subunit A	-

Sequence

Protein

• Length: 291 a.a.
• Molecular weight: 32419.67 Da
• Isoelectric Point: 7.1618

>NTDB_id=106919 AADG46_RS09850 WP_000418753.1 2179571..2180446(+) (pilD) [Vibrio cholerae strain VN152]
MELFYFYPWLFPVLATLFGLIVGSFLNVVIYRLPKIMEREWRAECAASFPEYGITPPEGKLTLSLPRSTCPHCQTPIRVI
DNIPLLSWLALRGQCSHCKAPISARYPLIELLTALMSLVIATHFPFGVFGVALLFFSYVLIAATFIDFDTLLLPDQLTLP
LLWGGIALALLGFSPVSLSDAVIGAMAGYLSLWSIYWLFKLLTGKEGMGYGDFKLLAALGAWLGWQQLPVIVLLSSVVGV
IFGLIQLRQQKKGIDMAFPFGPYLAIAGWFALLWGDKVIDWYFTTWVGQPL

Nucleotide

• Length: 876 bp

>NTDB_id=106919 AADG46_RS09850 WP_000418753.1 2179571..2180446(+) (pilD) [Vibrio cholerae strain VN152]
ATGGAACTGTTTTACTTCTACCCTTGGCTGTTTCCGGTGCTCGCCACGCTGTTTGGCTTGATTGTCGGCAGCTTTCTCAA
TGTGGTGATCTATCGCTTACCCAAAATCATGGAGCGTGAATGGCGTGCGGAATGTGCGGCGAGTTTTCCTGAATATGGCA
TCACGCCACCAGAGGGTAAACTGACCCTCAGTTTGCCGCGTTCCACTTGCCCACACTGCCAAACGCCGATTCGCGTGATT
GATAATATCCCGCTACTGAGTTGGCTGGCGCTGCGCGGTCAATGCTCACACTGTAAAGCGCCGATCAGCGCTCGTTATCC
CTTGATTGAGCTACTCACTGCCCTCATGAGCTTAGTGATTGCTACTCACTTTCCGTTTGGGGTGTTTGGCGTGGCGCTGC
TGTTTTTCAGCTATGTATTGATTGCGGCGACCTTCATCGACTTCGATACCCTGTTGCTGCCCGACCAATTAACGCTACCT
TTACTGTGGGGCGGTATTGCACTGGCACTGCTTGGCTTTTCTCCGGTTTCACTCAGTGATGCAGTGATCGGAGCCATGGC
GGGCTATCTCTCGCTGTGGTCGATTTACTGGCTATTTAAACTGCTGACAGGTAAAGAAGGCATGGGTTATGGCGATTTCA
AATTGCTCGCCGCACTCGGCGCTTGGCTGGGTTGGCAGCAGTTGCCTGTCATCGTACTGCTCTCATCGGTGGTCGGGGTG
ATTTTCGGTTTAATCCAACTGCGCCAGCAGAAAAAAGGTATTGATATGGCCTTTCCGTTTGGCCCTTATCTCGCCATCGC
GGGGTGGTTTGCCTTGCTGTGGGGCGATAAGGTAATTGATTGGTACTTCACCACTTGGGTAGGACAACCGTTATGA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (135-244)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	99.656	100	0.997
pilD	Vibrio campbellii strain DS40M4	75.347	98.969	0.746
pilD	Acinetobacter nosocomialis M2	53.676	93.471	0.502
pilD	Acinetobacter baumannii D1279779	53.309	93.471	0.498
pilD	Neisseria gonorrhoeae MS11	44.792	98.969	0.443