Detailed information NTG1069099

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACF1RT_RS07215
• Genome accession: NZ_CP172847
• Coordinates: 1445727..1447961 (-)
• Length: 744 a.a.
• NCBI ID: WP_226710906.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain DPC6143
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1440727..1452961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF1RT_RS07195 (ACF1RT_07195)	-	1441332..1442396 (-)	1065	WP_080035186.1	serine hydrolase	-
ACF1RT_RS07200 (ACF1RT_07200)	sodA	1442949..1443560 (-)	612	WP_002261912.1	superoxide dismutase SodA	-
ACF1RT_RS07205 (ACF1RT_07205)	holA	1443707..1444747 (-)	1041	WP_168752072.1	DNA polymerase III subunit delta	-
ACF1RT_RS07210 (ACF1RT_07210)	-	1444915..1445541 (-)	627	WP_002264731.1	DUF805 domain-containing protein	-
ACF1RT_RS07215 (ACF1RT_07215)	comEC/celB	1445727..1447961 (-)	2235	WP_226710906.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACF1RT_RS07220 (ACF1RT_07220)	-	1447951..1448631 (-)	681	WP_226710905.1	helix-hairpin-helix domain-containing protein	-
ACF1RT_RS07225 (ACF1RT_07225)	-	1448771..1449523 (-)	753	WP_002264733.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ACF1RT_RS07230 (ACF1RT_07230)	-	1449662..1450597 (+)	936	WP_019313136.1	polysaccharide deacetylase family protein	-
ACF1RT_RS07235 (ACF1RT_07235)	-	1450686..1451198 (+)	513	WP_002261919.1	HXXEE domain-containing protein	-
ACF1RT_RS07240 (ACF1RT_07240)	-	1451244..1452263 (+)	1020	WP_019313135.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85629.11 Da
• Isoelectric Point: 10.0891

>NTDB_id=1069099 ACF1RT_RS07215 WP_226710906.1 1445727..1447961(-) (comEC/celB) [Streptococcus mutans strain DPC6143]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSINGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSNFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISNKTILIDVGGKVTFGQTDKWRRRISDTNAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLLVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=1069099 ACF1RT_RS07215 WP_226710906.1 1445727..1447961(-) (comEC/celB) [Streptococcus mutans strain DPC6143]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGTTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTATCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTCACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTGCCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAATT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAATAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACTTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATACTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACTGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

• Competence protein (Competence) (214-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	51.147	99.597	0.509
comEC/celB	Streptococcus mitis NCTC 12261	51.078	99.731	0.509
comEC/celB	Streptococcus pneumoniae TIGR4	50.672	100	0.507
comEC/celB	Streptococcus pneumoniae Rx1	50	100	0.5
comEC/celB	Streptococcus pneumoniae D39	50	100	0.5
comEC/celB	Streptococcus pneumoniae R6	50	100	0.5
comEC	Lactococcus lactis subsp. cremoris KW2	46.309	100	0.464