Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ACF1RT_RS01450 Genome accession   NZ_CP172847
Coordinates   289353..290678 (+) Length   441 a.a.
NCBI ID   WP_400260324.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 284353..295678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS01425 (ACF1RT_01425) dnaI 284525..285424 (+) 900 WP_002267936.1 primosomal protein DnaI -
  ACF1RT_RS01430 (ACF1RT_01430) der 285437..286747 (+) 1311 WP_226711107.1 ribosome biogenesis GTPase Der -
  ACF1RT_RS01435 (ACF1RT_01435) - 286822..287448 (+) 627 WP_002268642.1 hypothetical protein -
  ACF1RT_RS01440 (ACF1RT_01440) - 287496..288134 (+) 639 WP_002271525.1 VTT domain-containing protein -
  ACF1RT_RS01445 (ACF1RT_01445) comE/blpR 288605..289360 (+) 756 WP_226711110.1 response regulator transcription factor Regulator
  ACF1RT_RS01450 (ACF1RT_01450) comD/blpH 289353..290678 (+) 1326 WP_400260324.1 sensor histidine kinase Regulator
  ACF1RT_RS01455 (ACF1RT_01455) comC/blpC 290820..290960 (-) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  ACF1RT_RS01460 (ACF1RT_01460) cipB 291227..291457 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  ACF1RT_RS01465 (ACF1RT_01465) - 291588..291989 (+) 402 WP_002310604.1 hypothetical protein -
  ACF1RT_RS01470 (ACF1RT_01470) - 293370..293789 (+) 420 WP_002263913.1 hypothetical protein -
  ACF1RT_RS01475 (ACF1RT_01475) - 293936..294340 (+) 405 WP_002263912.1 hypothetical protein -
  ACF1RT_RS01480 (ACF1RT_01480) - 294463..294675 (-) 213 Protein_267 IS3 family transposase -
  ACF1RT_RS01485 (ACF1RT_01485) - 295115..295279 (+) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50607.80 Da        Isoelectric Point: 9.7187

>NTDB_id=1069068 ACF1RT_RS01450 WP_400260324.1 289353..290678(+) (comD/blpH) [Streptococcus mutans strain DPC6143]
MNEVLMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYCLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPEMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSNHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1069068 ACF1RT_RS01450 WP_400260324.1 289353..290678(+) (comD/blpH) [Streptococcus mutans strain DPC6143]
ATGAATGAAGTTTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAACTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTGCCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGAGATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGTATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAATCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

98.866

100

0.989

Multiple sequence alignment