Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACF1RT_RS01410 Genome accession   NZ_CP172847
Coordinates   281816..282508 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 276816..287508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS01390 (ACF1RT_01390) - 276927..279539 (-) 2613 WP_019313431.1 ABC transporter permease -
  ACF1RT_RS01395 (ACF1RT_01395) - 279541..280248 (-) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  ACF1RT_RS01400 (ACF1RT_01400) - 280356..280931 (+) 576 WP_002265122.1 TetR/AcrR family transcriptional regulator -
  ACF1RT_RS01405 (ACF1RT_01405) - 280924..281460 (+) 537 WP_002262122.1 DUF177 domain-containing protein -
  ACF1RT_RS01410 (ACF1RT_01410) covR 281816..282508 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  ACF1RT_RS01415 (ACF1RT_01415) nrdR 282877..283368 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  ACF1RT_RS01420 (ACF1RT_01420) - 283355..284524 (+) 1170 WP_019313428.1 DnaD domain protein -
  ACF1RT_RS01425 (ACF1RT_01425) dnaI 284525..285424 (+) 900 WP_002267936.1 primosomal protein DnaI -
  ACF1RT_RS01430 (ACF1RT_01430) der 285437..286747 (+) 1311 WP_226711107.1 ribosome biogenesis GTPase Der -
  ACF1RT_RS01435 (ACF1RT_01435) - 286822..287448 (+) 627 WP_002268642.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=1069066 ACF1RT_RS01410 WP_002262121.1 281816..282508(+) (covR) [Streptococcus mutans strain DPC6143]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1069066 ACF1RT_RS01410 WP_002262121.1 281816..282508(+) (covR) [Streptococcus mutans strain DPC6143]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTAGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment