Detailed information NTG0106625

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: AABJ45_RS10685
• Genome accession: NZ_AP028611
• Coordinates: 2072578..2073285 (+)
• Length: 235 a.a.
• NCBI ID: WP_054381805.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep6
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2071466..2071855	2072578..2073285	flank	723

Gene organization within MGE regions

Location: 2071466..2073285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS10675	-	2071466..2072023 (-)	558	Protein_2064	transposase family protein	-
AABJ45_RS10680 (TKY121527_20800)	-	2072009..2072494 (+)	486	WP_001815029.1	cupin domain-containing protein	-
AABJ45_RS10685 (TKY121527_20810)	vicR	2072578..2073285 (+)	708	WP_054381805.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27212.58 Da
• Isoelectric Point: 6.6568

>NTDB_id=106625 AABJ45_RS10685 WP_054381805.1 2072578..2073285(+) (vicR) [Streptococcus pneumoniae strain Sep6]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLIKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide

• Length: 708 bp

>NTDB_id=106625 AABJ45_RS10685 WP_054381805.1 2072578..2073285(+) (vicR) [Streptococcus pneumoniae strain Sep6]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTGACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATAAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	48.707	98.723	0.481
micA	Streptococcus pneumoniae Cp1015	47.845	98.723	0.472
covR	Lactococcus lactis subsp. lactis strain DGCC12653	40.343	99.149	0.4
covR	Streptococcus salivarius strain HSISS4	39.744	99.574	0.396