Detailed information NTG0106552

Bioinformatically predicted

Overview

• Name: comFC/cflB
• Type: Machinery gene
• Locus tag: AABA16_RS10510
• Genome accession: NZ_AP028610
• Coordinates: 2032719..2033381 (-)
• Length: 220 a.a.
• NCBI ID: WP_000649971.1
• Uniprot ID: A0A0B7MFB3
• Organism: Streptococcus pneumoniae strain Sep5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2027719..2038381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA16_RS10485 (TKY124516_20270)	-	2027870..2028136 (-)	267	WP_001278167.1	Veg family protein	-
AABA16_RS10490 (TKY124516_20280)	dnaB	2028138..2029490 (-)	1353	WP_000852486.1	replicative DNA helicase	-
AABA16_RS10495 (TKY124516_20290)	rplI	2029533..2029985 (-)	453	WP_000864220.1	50S ribosomal protein L9	-
AABA16_RS10500 (TKY124516_20300)	-	2029982..2031955 (-)	1974	WP_000715108.1	DHH family phosphoesterase	-
AABA16_RS10505 (TKY124516_20310)	raiA	2032091..2032639 (-)	549	WP_000599104.1	ribosome-associated translation inhibitor RaiA	-
AABA16_RS10510 (TKY124516_20320)	comFC/cflB	2032719..2033381 (-)	663	WP_000649971.1	ComF family protein	Machinery gene
AABA16_RS10515 (TKY124516_20330)	comFA/cflA	2033378..2034676 (-)	1299	WP_000867612.1	DEAD/DEAH box helicase	Machinery gene
AABA16_RS10520 (TKY124516_20340)	-	2034732..2035367 (+)	636	WP_000395739.1	YigZ family protein	-
AABA16_RS10525 (TKY124516_20350)	cysK	2035652..2036572 (+)	921	WP_000029867.1	cysteine synthase A	-
AABA16_RS10530	-	2036811..2037176 (-)	366	Protein_2035	IS66 family transposase	-
AABA16_RS10535 (TKY124516_20370)	-	2037158..2037445 (+)	288	Protein_2036	transposase	-
AABA16_RS10540 (TKY124516_20380)	tnpB	2037586..2037840 (-)	255	WP_061747476.1	IS66 family insertion sequence element accessory protein TnpB	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 25241.10 Da
• Isoelectric Point: 7.3688

>NTDB_id=106552 AABA16_RS10510 WP_000649971.1 2032719..2033381(-) (comFC/cflB) [Streptococcus pneumoniae strain Sep5]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide

• Length: 663 bp

>NTDB_id=106552 AABA16_RS10510 WP_000649971.1 2032719..2033381(-) (comFC/cflB) [Streptococcus pneumoniae strain Sep5]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGACTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

• Phosphoribosyl transferase domain (Pribosyltran) (153-219)

3D structure

• AlphaFold DB: A0A0B7MFB3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC/cflB	Streptococcus pneumoniae TIGR4	100	100	1
comFC/cflB	Streptococcus pneumoniae Rx1	99.545	100	0.995
comFC/cflB	Streptococcus pneumoniae D39	99.545	100	0.995
comFC/cflB	Streptococcus pneumoniae R6	99.545	100	0.995
comFC/cflB	Streptococcus mitis NCTC 12261	91.818	100	0.918
comFC/cflB	Streptococcus mitis SK321	91.364	100	0.914