Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   AABA19_RS10070 Genome accession   NZ_AP028609
Coordinates   1948973..1949680 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1943973..1954680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS10050 (TKY121806_19450) argR 1945291..1945737 (-) 447 WP_001231472.1 arginine repressor -
  AABA19_RS10055 (TKY121806_19460) argS 1945873..1947564 (+) 1692 WP_001092739.1 arginine--tRNA ligase -
  AABA19_RS10060 - 1947879..1948418 (-) 540 Protein_1943 transposase family protein -
  AABA19_RS10065 (TKY121806_19480) - 1948413..1948889 (+) 477 WP_000356601.1 cupin domain-containing protein -
  AABA19_RS10070 (TKY121806_19490) vicR 1948973..1949680 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  AABA19_RS10075 (TKY121806_19500) pnpS 1949681..1951012 (+) 1332 WP_000833277.1 two-component system histidine kinase PnpS -
  AABA19_RS10080 (TKY121806_19510) - 1951179..1952054 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  AABA19_RS10085 (TKY121806_19520) pstC 1952172..1953035 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  AABA19_RS10090 (TKY121806_19530) pstA 1953028..1953843 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  AABA19_RS10095 (TKY121806_19540) pstB 1953845..1954597 (+) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=106471 AABA19_RS10070 WP_000166475.1 1948973..1949680(+) (vicR) [Streptococcus pneumoniae strain Sep4]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=106471 AABA19_RS10070 WP_000166475.1 1948973..1949680(+) (vicR) [Streptococcus pneumoniae strain Sep4]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396

Multiple sequence alignment