Detailed information NTG0106444

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: AABA19_RS08555
• Genome accession: NZ_AP028609
• Coordinates: 1689969..1690628 (+)
• Length: 219 a.a.
• NCBI ID: WP_061634891.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep4
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1684969..1695628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS08530 (TKY121806_16960)	-	1685274..1685591 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
AABA19_RS08535 (TKY121806_16970)	-	1685606..1686502 (-)	897	WP_000825665.1	PEP phosphonomutase	-
AABA19_RS08540 (TKY121806_16980)	-	1686505..1687767 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
AABA19_RS08545 (TKY121806_16990)	-	1688047..1689225 (+)	1179	WP_000175876.1	ROK family transcriptional regulator	-
AABA19_RS08550 (TKY121806_17000)	-	1689453..1689899 (-)	447	WP_000155427.1	GNAT family N-acetyltransferase	-
AABA19_RS08555 (TKY121806_17010)	cclA/cilC	1689969..1690628 (+)	660	WP_061634891.1	prepilin peptidase	Machinery gene
AABA19_RS08560 (TKY121806_17020)	-	1690680..1691831 (-)	1152	WP_000481750.1	helix-turn-helix domain-containing protein	-
AABA19_RS08565 (TKY121806_17030)	-	1691846..1692577 (-)	732	WP_000934017.1	hypothetical protein	-
AABA19_RS08570	-	1692797..1692907 (+)	111	Protein_1698	prepilin peptidase	-
AABA19_RS08575 (TKY121806_17040)	trpA	1692879..1693655 (-)	777	WP_001127048.1	tryptophan synthase subunit alpha	-
AABA19_RS08580 (TKY121806_17050)	trpB	1693648..1694871 (-)	1224	WP_000331287.1	tryptophan synthase subunit beta	-
AABA19_RS08585 (TKY121806_17060)	-	1694849..1695448 (-)	600	WP_277770329.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24842.93 Da
• Isoelectric Point: 7.6165

>NTDB_id=106444 AABA19_RS08555 WP_061634891.1 1689969..1690628(+) (cclA/cilC) [Streptococcus pneumoniae strain Sep4]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLG
LLFLLYSWGWLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=106444 AABA19_RS08555 WP_061634891.1 1689969..1690628(+) (cclA/cilC) [Streptococcus pneumoniae strain Sep4]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAAGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	99.543	100	0.995
cclA/cilC	Streptococcus pneumoniae Rx1	94.521	100	0.945
cclA/cilC	Streptococcus pneumoniae D39	94.521	100	0.945
cclA/cilC	Streptococcus pneumoniae R6	94.521	100	0.945
cclA/cilC	Streptococcus mitis SK321	91.324	100	0.913
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868