Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACG3JK_RS05555 Genome accession   NZ_CP171738
Coordinates   1113608..1114294 (-) Length   228 a.a.
NCBI ID   WP_003104116.1    Uniprot ID   A0A0E2UE77
Organism   Streptococcus parauberis strain DB-M23     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1108608..1119294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JK_RS05535 (ACG3JK_05535) dnaI 1109393..1110295 (-) 903 WP_003103419.1 primosomal protein DnaI -
  ACG3JK_RS05540 (ACG3JK_05540) - 1110296..1111480 (-) 1185 WP_003106211.1 DnaD domain protein -
  ACG3JK_RS05545 (ACG3JK_05545) nrdR 1111464..1111958 (-) 495 WP_003105627.1 transcriptional regulator NrdR -
  ACG3JK_RS05550 (ACG3JK_05550) - 1112086..1113606 (-) 1521 WP_394714118.1 ATP-binding protein -
  ACG3JK_RS05555 (ACG3JK_05555) covR 1113608..1114294 (-) 687 WP_003104116.1 two-component system response regulator CovR Regulator
  ACG3JK_RS05560 (ACG3JK_05560) - 1114550..1115083 (-) 534 WP_003102943.1 DUF177 domain-containing protein -
  ACG3JK_RS05565 (ACG3JK_05565) htpX 1115209..1116105 (-) 897 WP_003106209.1 zinc metalloprotease HtpX -
  ACG3JK_RS05570 (ACG3JK_05570) - 1116137..1116694 (-) 558 WP_003103300.1 LemA family protein -
  ACG3JK_RS05575 (ACG3JK_05575) rsmG 1116838..1117551 (+) 714 WP_003104507.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ACG3JK_RS05580 (ACG3JK_05580) - 1117636..1119012 (+) 1377 WP_013794297.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26596.58 Da        Isoelectric Point: 4.6586

>NTDB_id=1064071 ACG3JK_RS05555 WP_003104116.1 1113608..1114294(-) (covR) [Streptococcus parauberis strain DB-M23]
MTKKILIVEDEKNLARFVSLELQHEGYEVSVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMTNMNRVMTREELLSSVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1064071 ACG3JK_RS05555 WP_003104116.1 1113608..1114294(-) (covR) [Streptococcus parauberis strain DB-M23]
ATGACTAAGAAAATTTTAATTGTTGAAGACGAAAAGAATCTAGCAAGATTTGTTTCTCTTGAATTACAACATGAAGGCTA
TGAAGTTAGTGTTGAAGTAAACGGTAGAGAAGGACTTGAAACTGCATTAGAAAAAGATTTTGATTTAATTCTGCTTGACT
TAATGCTTCCTGAGATGGATGGTTTTGAAGTTACTCGCCGCTTACAAACAGAAAAAACAACTTATATCATGATGATGACT
GCGCGTGATTCAATCATGGATGTTGTTGCAGGTCTTGACCGTGGTGCGGATGACTATATCGTAAAACCTTTTGCGATTGA
AGAATTGTTGGCACGTATTCGTGCAATCTTCCGTCGACAAGATATCGAAACTGAGAAGAAAGCGCCAAATCAAGGCGTTT
ACCGCGATTTAGTGTTAAATCCTCAAAATCGTTCAGTTAATCGTGGAGATGAAGAAATTTCATTAACAAAACGTGAATAT
GATTTATTAAATATTTTGATGACTAATATGAACCGTGTTATGACTCGTGAAGAGTTATTATCAAGTGTATGGAAGTATGA
TGAAGCTGTTGAAACAAACGTAGTTGATGTTTATATTCGTTATCTTCGTGGCAAAATTGATATGCCAGGAAGAGAATCTT
ACATCCAAACAGTTCGTGGAATGGGATATGTAATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UE77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

83.406

100

0.838
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.439

Multiple sequence alignment