Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   AABA07_RS10385 Genome accession   NZ_AP028608
Coordinates   2034439..2035764 (-) Length   441 a.a.
NCBI ID   WP_338172752.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep3     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2029439..2040764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA07_RS10360 - 2031123..2032726 (-) 1604 Protein_2001 YhgE/Pip domain-containing protein -
  AABA07_RS10365 (TKY120829_20150) - 2032905..2033447 (+) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  AABA07_RS10380 (TKY120829_20160) comE 2033690..2034442 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  AABA07_RS10385 (TKY120829_20170) comD/comD1 2034439..2035764 (-) 1326 WP_338172752.1 competence system sensor histidine kinase ComD Regulator
  AABA07_RS10390 (TKY120829_20180) comC/comC1 2035785..2035910 (-) 126 WP_000799689.1 competence-stimulating peptide ComC Regulator
  AABA07_RS10400 (TKY120829_20190) rlmH 2036192..2036671 (-) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AABA07_RS10405 (TKY120829_20200) htrA 2036854..2038035 (+) 1182 WP_000681597.1 trypsin-like peptidase domain-containing protein Regulator
  AABA07_RS10410 (TKY120829_20210) spo0J 2038093..2038851 (+) 759 WP_000410378.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51413.83 Da        Isoelectric Point: 6.6400

>NTDB_id=106401 AABA07_RS10385 WP_338172752.1 2034439..2035764(-) (comD/comD1) [Streptococcus pneumoniae strain Sep3]
MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTEIVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVSLY
NEIRGFRHDYAGMLVSMQMAIDSSNLQEIDRIYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=106401 AABA07_RS10385 WP_338172752.1 2034439..2035764(-) (comD/comD1) [Streptococcus pneumoniae strain Sep3]
ATGGATTTATTTGGATTTGGGACGGTTATTGTTCATTTTTTAATTATTAGTCACAGTTACCATTTTATTTGTAAAGGTCA
AATAAATAGAAAAGAATTATTCGTTTTTGGTGCTTATACATTACTAACAGAAATAGTATTTGATTTTCCCTTATATATTC
TATATTTAGATGGGTTAGGGATTGAAAGATTTTTATTTCCTTTGGGATTATATTCCTATTTTCGATGGATGAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCCTCTATAACAGGAGATAATTTTGTTTTACAATATCATTTCCCATTCTTTTTCGTTGTGACGGTGTTAACCTATTTTG
TTACATTAAAAATCATTTACTATTTCCATTTGGAACTAGCCTATTTTGACGAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATCTCTCTCCTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTACACAGATGAAATTGTTAGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTAGTAATTTACA
GGAAATTGACAGAATTTACAATGAAGTTTTAGTCAAAGCAAATCATAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGACTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATTGAACTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
TAATGCTGTCGAAGGATCGGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

99.546

100

0.995
  comD/comD1 Streptococcus pneumoniae D39

99.546

100

0.995
  comD/comD1 Streptococcus pneumoniae R6

99.546

100

0.995
  comD/comD2 Streptococcus pneumoniae TIGR4

96.372

100

0.964
  comD Streptococcus mitis SK321

91.61

100

0.916
  comD Streptococcus mitis NCTC 12261

85.714

100

0.857
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.198

84.807

0.417
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.936

85.261

0.417

Multiple sequence alignment