Detailed information NTG0106365

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: AABA07_RS08075
• Genome accession: NZ_AP028608
• Coordinates: 1600394..1601053 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565010.1
• Uniprot ID: A0A0B7M2C6
• Organism: Streptococcus pneumoniae strain Sep3
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1595394..1606053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA07_RS08050 (TKY120829_16000)	-	1595699..1596016 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
AABA07_RS08055 (TKY120829_16010)	-	1596031..1596927 (-)	897	WP_000825669.1	PEP phosphonomutase	-
AABA07_RS08060 (TKY120829_16020)	-	1596930..1598192 (-)	1263	WP_000413345.1	PTS sugar transporter subunit IIC	-
AABA07_RS08065 (TKY120829_16030)	-	1598472..1599650 (+)	1179	WP_000175876.1	ROK family transcriptional regulator	-
AABA07_RS08070 (TKY120829_16040)	-	1599878..1600324 (-)	447	WP_000155418.1	GNAT family N-acetyltransferase	-
AABA07_RS08075 (TKY120829_16050)	cclA/cilC	1600394..1601053 (+)	660	WP_000565010.1	A24 family peptidase	Machinery gene
AABA07_RS08080 (TKY120829_16060)	trpA	1601025..1601801 (-)	777	WP_001126994.1	tryptophan synthase subunit alpha	-
AABA07_RS08085 (TKY120829_16070)	trpB	1601794..1603017 (-)	1224	WP_000331292.1	tryptophan synthase subunit beta	-
AABA07_RS08090 (TKY120829_16080)	-	1602995..1603594 (-)	600	WP_000169893.1	phosphoribosylanthranilate isomerase	-
AABA07_RS08095 (TKY120829_16090)	trpC	1603581..1604348 (-)	768	WP_000076558.1	indole-3-glycerol phosphate synthase TrpC	-
AABA07_RS08100 (TKY120829_16100)	trpD	1604345..1605349 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
AABA07_RS08105 (TKY120829_16110)	-	1605360..1605926 (-)	567	WP_000601927.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24845.99 Da
• Isoelectric Point: 7.5762

>NTDB_id=106365 AABA07_RS08075 WP_000565010.1 1600394..1601053(+) (cclA/cilC) [Streptococcus pneumoniae strain Sep3]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=106365 AABA07_RS08075 WP_000565010.1 1600394..1601053(+) (cclA/cilC) [Streptococcus pneumoniae strain Sep3]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	100	100	1
cclA/cilC	Streptococcus pneumoniae D39	100	100	1
cclA/cilC	Streptococcus pneumoniae R6	100	100	1
cclA/cilC	Streptococcus pneumoniae TIGR4	94.977	100	0.95
cclA/cilC	Streptococcus mitis SK321	92.694	100	0.927
cclA/cilC	Streptococcus mitis NCTC 12261	87.671	100	0.877