Detailed information NTG0106316

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: AABA14_RS10360
• Genome accession: NZ_AP028607
• Coordinates: 1975478..1976185 (+)
• Length: 235 a.a.
• NCBI ID: WP_277771880.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep2
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1974365..1974754	1975478..1976185	flank	724

Gene organization within MGE regions

Location: 1974365..1976185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA14_RS10350	-	1974365..1974922 (-)	558	Protein_1998	transposase family protein	-
AABA14_RS10355	-	1974908..1975394 (+)	487	Protein_1999	cupin domain-containing protein	-
AABA14_RS10360 (TKY123642_20080)	vicR	1975478..1976185 (+)	708	WP_277771880.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27212.58 Da
• Isoelectric Point: 6.6568

>NTDB_id=106316 AABA14_RS10360 WP_277771880.1 1975478..1976185(+) (vicR) [Streptococcus pneumoniae strain Sep2]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIIMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide

• Length: 708 bp

>NTDB_id=106316 AABA14_RS10360 WP_277771880.1 1975478..1976185(+) (vicR) [Streptococcus pneumoniae strain Sep2]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATTATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	49.138	98.723	0.485
micA	Streptococcus pneumoniae Cp1015	47.845	98.723	0.472
covR	Lactococcus lactis subsp. lactis strain DGCC12653	41.202	99.149	0.409
covR	Streptococcus salivarius strain HSISS4	39.316	99.574	0.391