Detailed information NTG0106274

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AABA14_RS04620
• Genome accession: NZ_AP028607
• Coordinates: 893281..894234 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain Sep2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 888281..899234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA14_RS04595	rpmG	889024..889173 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
AABA14_RS04600 (TKY123642_08940)	secG	889213..889446 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
AABA14_RS04605 (TKY123642_08950)	rnr	889548..891902 (+)	2355	WP_061742425.1	ribonuclease R	-
AABA14_RS04610 (TKY123642_08960)	smpB	891865..892332 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
AABA14_RS04615 (TKY123642_08970)	tehB	892348..893208 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
AABA14_RS04620 (TKY123642_08980)	coiA	893281..894234 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
AABA14_RS04625 (TKY123642_08990)	pepF	894253..896055 (+)	1803	WP_001864211.1	oligoendopeptidase F	Regulator
AABA14_RS04630 (TKY123642_09000)	-	896057..896770 (+)	714	WP_000230399.1	O-methyltransferase	-
AABA14_RS04635 (TKY123642_09010)	prsA	896837..897778 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
AABA14_RS04640 (TKY123642_09020)	-	897895..898236 (-)	342	Protein_915	IS3 family transposase	-
AABA14_RS04645	-	898648..898743 (+)	96	Protein_916	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=106274 AABA14_RS04620 WP_000495909.1 893281..894234(+) (coiA) [Streptococcus pneumoniae strain Sep2]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=106274 AABA14_RS04620 WP_000495909.1 893281..894234(+) (coiA) [Streptococcus pneumoniae strain Sep2]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435