Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACF3N8_RS06020 Genome accession   NZ_CP171119
Coordinates   1256395..1257024 (+) Length   209 a.a.
NCBI ID   WP_009384035.1    Uniprot ID   K9AZ97
Organism   Staphylococcus massiliensis strain WGS1515     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1251395..1262024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF3N8_RS05995 (ACF3N8_05995) - 1252187..1253215 (-) 1029 WP_009384040.1 aromatic acid exporter family protein -
  ACF3N8_RS06000 (ACF3N8_06000) map 1253402..1254160 (+) 759 WP_009384039.1 type I methionyl aminopeptidase -
  ACF3N8_RS06005 (ACF3N8_06005) - 1254263..1254649 (+) 387 WP_017176866.1 hypothetical protein -
  ACF3N8_RS06010 (ACF3N8_06010) liaF 1254664..1255365 (+) 702 WP_238101028.1 cell wall-active antibiotics response protein LiaF -
  ACF3N8_RS06015 (ACF3N8_06015) vraS 1255362..1256405 (+) 1044 WP_009384036.1 sensor histidine kinase Regulator
  ACF3N8_RS06020 (ACF3N8_06020) vraR 1256395..1257024 (+) 630 WP_009384035.1 response regulator transcription factor Regulator
  ACF3N8_RS06025 (ACF3N8_06025) - 1257690..1258262 (-) 573 WP_392449764.1 beta-class carbonic anhydrase -
  ACF3N8_RS06030 (ACF3N8_06030) - 1258277..1259383 (-) 1107 WP_009384033.1 YihY/virulence factor BrkB family protein -
  ACF3N8_RS06035 (ACF3N8_06035) - 1259500..1259799 (-) 300 WP_009384032.1 YtxH domain-containing protein -
  ACF3N8_RS06040 (ACF3N8_06040) - 1259784..1260257 (-) 474 WP_009384031.1 low molecular weight protein-tyrosine-phosphatase -
  ACF3N8_RS06045 (ACF3N8_06045) - 1260401..1260604 (+) 204 WP_238094244.1 DUF1128 family protein -
  ACF3N8_RS06050 (ACF3N8_06050) - 1260617..1261846 (+) 1230 WP_238101030.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23638.22 Da        Isoelectric Point: 4.8783

>NTDB_id=1060228 ACF3N8_RS06020 WP_009384035.1 1256395..1257024(+) (vraR) [Staphylococcus massiliensis strain WGS1515]
MPIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGNDAIEKAKTLKPDLILMDLVMNDMDGVEATTHIKKEMPHIKVL
MLTSYIEDQEVYRALDAGVDSYILKTTSASDIANAIRKTYEGESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1060228 ACF3N8_RS06020 WP_009384035.1 1256395..1257024(+) (vraR) [Staphylococcus massiliensis strain WGS1515]
ATGCCAATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGAATATCAAGTTACTTATCGACACAATCTGA
TATTGAGGTTGTAGGTGAAGGTGAATCTGGTAACGATGCGATTGAAAAAGCGAAGACATTAAAGCCTGACTTAATCTTGA
TGGATCTTGTTATGAACGATATGGATGGAGTTGAAGCTACGACTCATATTAAAAAGGAAATGCCTCATATAAAAGTGTTG
ATGCTTACAAGTTACATTGAAGATCAAGAAGTATACCGCGCGCTTGATGCTGGCGTTGATAGCTATATTCTCAAAACTAC
GAGCGCTAGTGATATCGCGAATGCGATTCGTAAGACGTATGAAGGTGAATCCGTGTTTGAAGCGGAAGTTTTAGTTAAAA
TGCGTAACCGTATGAAGCAACGTGCTGAACTATATGAAATGCTGACTGAACGTGAAATGGAAATTCTGTTGTTAATCGCA
AAAGGGTACTCTAACCAGGAAATTGCAAGTGCCTCTCACATTACGATTAAGACAGTTAAAACGCATGTTAGTAATATATT
AAGTAAGCTTGAGGTTCAAGACCGTACGCAGGCGGTAATTTATGCTTTCCAACATAACTTAATTCAGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K9AZ97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.474

100

0.895
  letA Legionella pneumophila str. Paris

36.364

100

0.364
  letA Legionella pneumophila strain ERS1305867

36.364

100

0.364

Multiple sequence alignment