Detailed information NTG0105824

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AAA982_RS08620
• Genome accession: NZ_AP028601
• Coordinates: 1687886..1688953 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain PF1
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1682886..1693953

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA982_RS08595 (TKY113292_17010)	treR	1683056..1683766 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
AAA982_RS08600 (TKY113292_17020)	-	1683799..1684602 (-)	804	WP_115254439.1	ATP-binding cassette domain-containing protein	-
AAA982_RS08605 (TKY113292_17030)	-	1684615..1685508 (-)	894	WP_130894676.1	ABC transporter permease	-
AAA982_RS08610	-	1685520..1686458 (-)	939	Protein_1704	ABC transporter substrate-binding protein	-
AAA982_RS08615 (TKY113292_17060)	amiF	1686949..1687875 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
AAA982_RS08620 (TKY113292_17070)	amiE	1687886..1688953 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
AAA982_RS08625 (TKY113292_17080)	amiD	1688962..1689888 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
AAA982_RS08630 (TKY113292_17100)	-	1689888..1691290 (-)	1403	Protein_1708	ABC transporter permease	-
AAA982_RS08635 (TKY113292_17110)	amiA	1692156..1693160 (-)	1005	WP_338168272.1	ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=105824 AAA982_RS08620 WP_000159553.1 1687886..1688953(-) (amiE) [Streptococcus pneumoniae strain PF1]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=105824 AAA982_RS08620 WP_000159553.1 1687886..1688953(-) (amiE) [Streptococcus pneumoniae strain PF1]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541