Detailed information NTG0105805

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AAA982_RS04560
• Genome accession: NZ_AP028601
• Coordinates: 889333..891573 (+)
• Length: 746 a.a.
• NCBI ID: WP_023396235.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PF1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 884333..896573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA982_RS04525 (TKY113292_08870)	pyrH	884423..885160 (+)	738	WP_000002997.1	UMP kinase	-
AAA982_RS04530 (TKY113292_08880)	frr	885169..885726 (+)	558	WP_000024409.1	ribosome recycling factor	-
AAA982_RS04535 (TKY113292_08890)	cvfB	885786..886640 (+)	855	WP_317649393.1	RNA-binding virulence regulatory protein CvfB	-
AAA982_RS04540 (TKY113292_08900)	-	886649..886864 (+)	216	WP_001232085.1	YozE family protein	-
AAA982_RS04545 (TKY113292_08910)	-	886950..887954 (+)	1005	WP_000658185.1	PhoH family protein	-
AAA982_RS04550 (TKY113292_08920)	-	888062..888631 (+)	570	WP_000443751.1	GNAT family N-acetyltransferase	-
AAA982_RS04555 (TKY113292_08930)	comEA/celA/cilE	888699..889349 (+)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
AAA982_RS04560 (TKY113292_08940)	comEC/celB	889333..891573 (+)	2241	WP_023396235.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAA982_RS04565 (TKY113292_08950)	-	891752..891940 (+)	189	WP_023396236.1	hypothetical protein	-
AAA982_RS04570 (TKY113292_08960)	-	891972..892559 (+)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
AAA982_RS04575 (TKY113292_08970)	-	892563..893744 (+)	1182	WP_000655945.1	hypothetical protein	-
AAA982_RS04580 (TKY113292_08980)	infC	894051..894581 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
AAA982_RS04585 (TKY113292_08990)	rpmI	894614..894814 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
AAA982_RS04590 (TKY113292_09000)	rplT	894866..895225 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
AAA982_RS04595 (TKY113292_09010)	-	895283..895663 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84516.96 Da
• Isoelectric Point: 9.5181

>NTDB_id=105805 AAA982_RS04560 WP_023396235.1 889333..891573(+) (comEC/celB) [Streptococcus pneumoniae strain PF1]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
ENVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGVDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=105805 AAA982_RS04560 WP_023396235.1 889333..891573(+) (comEC/celB) [Streptococcus pneumoniae strain PF1]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGAATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGACGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGACACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGGTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.989	100	0.98
comEC/celB	Streptococcus pneumoniae D39	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae R6	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae Rx1	97.721	100	0.977
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44