Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DYB47_RS07530 Genome accession   NZ_UHFV01000002
Coordinates   1508840..1509490 (+) Length   216 a.a.
NCBI ID   WP_003080375.1    Uniprot ID   G5JW08
Organism   Streptococcus macacae NCTC 11558     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1503840..1514490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS07500 (NCTC11558_01522) - 1503937..1504203 (-) 267 WP_003081387.1 DUF3165 family protein -
  DYB47_RS07505 (NCTC11558_01523) typA 1504234..1506078 (-) 1845 WP_003082058.1 translational GTPase TypA -
  DYB47_RS07510 (NCTC11558_01524) - 1506347..1506736 (-) 390 WP_003081477.1 rhodanese-like domain-containing protein -
  DYB47_RS07515 (NCTC11558_01525) - 1506747..1507718 (-) 972 WP_003079242.1 ROK family glucokinase -
  DYB47_RS07520 (NCTC11558_01526) - 1507693..1507917 (-) 225 WP_040841817.1 YqgQ family protein -
  DYB47_RS07525 (NCTC11558_01527) dpr 1508210..1508737 (-) 528 WP_003081935.1 DNA starvation/stationary phase protection protein -
  DYB47_RS07530 (NCTC11558_01528) cclA/cilC 1508840..1509490 (+) 651 WP_003080375.1 prepilin peptidase Machinery gene
  DYB47_RS07535 (NCTC11558_01529) trpA 1509517..1510299 (-) 783 WP_003081730.1 tryptophan synthase subunit alpha -
  DYB47_RS07540 (NCTC11558_01530) trpB 1510304..1511512 (-) 1209 WP_003081533.1 tryptophan synthase subunit beta -
  DYB47_RS07545 (NCTC11558_01531) - 1511509..1512090 (-) 582 WP_003079137.1 phosphoribosylanthranilate isomerase -
  DYB47_RS07550 (NCTC11558_01532) trpC 1512077..1512844 (-) 768 WP_003081519.1 indole-3-glycerol phosphate synthase TrpC -
  DYB47_RS07555 (NCTC11558_01533) trpD 1512837..1513844 (-) 1008 WP_040841821.1 anthranilate phosphoribosyltransferase -
  DYB47_RS07560 (NCTC11558_01534) - 1513867..1514430 (-) 564 WP_003081634.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24892.92 Da        Isoelectric Point: 7.7761

>NTDB_id=1056485 DYB47_RS07530 WP_003080375.1 1508840..1509490(+) (cclA/cilC) [Streptococcus macacae NCTC 11558]
MKFFLFFCLGSSLGSFIGLIIDRFPEKSIIFPNSYCNYCKHSLAPRDLIPILSQIINKNRCRFCGYPIPFHYLLLELFCG
SICLLYANGCFSFSQLILLFMGILLSLYDLKDHSYPIIFWLAFTFFLMVFYPLNLISLFLFFLGLYAALKNIQIGSGDLL
YLSTLALSLNFQEILWVVQIASLLGIVYYLFCKKEESPIAFVPFLFSGYIAVLFFL

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1056485 DYB47_RS07530 WP_003080375.1 1508840..1509490(+) (cclA/cilC) [Streptococcus macacae NCTC 11558]
ATGAAATTCTTTTTATTTTTTTGTCTAGGAAGTTCCCTTGGCTCTTTTATTGGTTTGATTATTGATCGTTTTCCTGAAAA
ATCAATTATCTTCCCAAACAGTTACTGCAATTACTGTAAACATTCTTTAGCTCCAAGAGATCTGATTCCAATACTGTCAC
AAATAATCAATAAAAACCGCTGCCGCTTTTGCGGATACCCCATCCCTTTTCATTATTTACTGTTAGAATTGTTTTGCGGC
TCTATTTGCCTCCTGTATGCAAATGGCTGCTTTTCCTTTTCACAACTGATTTTGCTTTTTATGGGGATTCTCTTATCTCT
CTATGATTTGAAAGATCATTCCTATCCTATCATTTTCTGGCTTGCTTTTACTTTCTTTTTAATGGTTTTCTATCCTTTAA
ATCTTATCAGCCTTTTTCTTTTCTTTCTAGGTCTTTATGCTGCTCTTAAAAATATTCAAATCGGCAGCGGAGACTTACTT
TATTTATCGACTCTAGCTCTTTCTCTTAATTTTCAGGAAATATTATGGGTTGTTCAGATAGCAAGTCTACTAGGCATTGT
TTATTACCTTTTCTGCAAAAAAGAAGAAAGTCCCATCGCCTTTGTTCCTTTTTTATTTTCTGGCTATATTGCTGTCCTTT
TCTTTTTATAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JW08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

44.498

96.759

0.431
  cclA/cilC Streptococcus mitis NCTC 12261

42.584

96.759

0.412
  cclA/cilC Streptococcus pneumoniae Rx1

42.18

97.685

0.412
  cclA/cilC Streptococcus pneumoniae D39

42.18

97.685

0.412
  cclA/cilC Streptococcus pneumoniae R6

42.18

97.685

0.412
  cclA/cilC Streptococcus pneumoniae TIGR4

43.564

93.519

0.407