NTDB

Overview

Name	cclA/cilC	Type	Machinery gene
Locus tag	ACLV65_RS02345	Genome accession	NZ_OZ217342
Coordinates	449735..450394 (-)	Length	219 a.a.
NCBI ID	WP_000565023.1	Uniprot ID	-
Organism	Streptococcus mitis isolate S. mitis B22
Function	processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 444735..455394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV65_RS02315 (SMIB22_04460)	-	444862..445428 (+)	567	WP_411864419.1	aminodeoxychorismate/anthranilate synthase component II	-
ACLV65_RS02320 (SMIB22_04470)	trpD	445439..446443 (+)	1005	WP_411864420.1	anthranilate phosphoribosyltransferase	-
ACLV65_RS02325 (SMIB22_04480)	trpC	446440..447207 (+)	768	WP_000076544.1	indole-3-glycerol phosphate synthase TrpC	-
ACLV65_RS02330 (SMIB22_04490)	-	447194..447793 (+)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
ACLV65_RS02335 (SMIB22_04500)	trpB	447771..448994 (+)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
ACLV65_RS02340 (SMIB22_04510)	trpA	448987..449763 (+)	777	WP_001127007.1	tryptophan synthase subunit alpha	-
ACLV65_RS02345 (SMIB22_04520)	cclA/cilC	449735..450394 (-)	660	WP_000565023.1	prepilin peptidase	Machinery gene
ACLV65_RS02350 (SMIB22_04530)	-	450464..450910 (+)	447	WP_000155406.1	GNAT family N-acetyltransferase	-
ACLV65_RS02355 (SMIB22_04540)	-	451138..452316 (-)	1179	WP_000175880.1	ROK family transcriptional regulator	-
ACLV65_RS02360 (SMIB22_04550)	-	452596..453858 (+)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
ACLV65_RS02365 (SMIB22_04560)	-	453861..454757 (+)	897	WP_000825669.1	PEP phosphonomutase	-
ACLV65_RS02370 (SMIB22_04570)	-	454772..455089 (+)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-

Sequence

Protein

Download Length: 219 a.a. Molecular weight: 24921.13 Da Isoelectric Point: 8.2409

                                >NTDB_id=1055845 ACLV65_RS02345 WP_000565023.1 449735..450394(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis B22]

MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG

LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL

FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

Download Length: 660 bp

                                >NTDB_id=1055845 ACLV65_RS02345 WP_000565023.1 449735..450394(-) (cclA/cilC) [Streptococcus mitis isolate S. mitis B22]

ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA

ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC

AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA

CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTAGTCCTAATCACCGCTGGTTTGACCTTGGGTAT

CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA

ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC

TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT

GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG

GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863

Detailed information NTG1055845