Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACE2AN_RS08165 Genome accession   NZ_CP169564
Coordinates   1634029..1634688 (+) Length   219 a.a.
NCBI ID   WP_001866459.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1629029..1639688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS08140 - 1629334..1629651 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  ACE2AN_RS08145 - 1629666..1630562 (-) 897 WP_000825663.1 PEP phosphonomutase -
  ACE2AN_RS08150 - 1630565..1631827 (-) 1263 WP_000413345.1 PTS sugar transporter subunit IIC -
  ACE2AN_RS08155 - 1632107..1633285 (+) 1179 WP_001866460.1 ROK family transcriptional regulator -
  ACE2AN_RS08160 - 1633513..1633959 (-) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  ACE2AN_RS08165 cclA/cilC 1634029..1634688 (+) 660 WP_001866459.1 A24 family peptidase Machinery gene
  ACE2AN_RS08170 - 1634740..1635891 (-) 1152 WP_001866458.1 ImmA/IrrE family metallo-endopeptidase -
  ACE2AN_RS08175 - 1635906..1636637 (-) 732 WP_081528473.1 hypothetical protein -
  ACE2AN_RS08180 - 1636857..1636967 (+) 111 Protein_1618 prepilin peptidase -
  ACE2AN_RS08185 trpA 1636939..1637715 (-) 777 WP_081528474.1 tryptophan synthase subunit alpha -
  ACE2AN_RS08190 trpB 1637708..1638931 (-) 1224 WP_081528475.1 tryptophan synthase subunit beta -
  ACE2AN_RS08195 - 1638909..1639508 (-) 600 WP_180377275.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24827.91 Da        Isoelectric Point: 7.6166

>NTDB_id=1052194 ACE2AN_RS08165 WP_001866459.1 1634029..1634688(+) (cclA/cilC) [Streptococcus pneumoniae strain 6_2F1]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1052194 ACE2AN_RS08165 WP_001866459.1 1634029..1634688(+) (cclA/cilC) [Streptococcus pneumoniae strain 6_2F1]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTACCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae TIGR4

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment