Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ABJR17_RS05335 Genome accession   NZ_CP169357
Coordinates   1122911..1124107 (-) Length   398 a.a.
NCBI ID   WP_006248403.1    Uniprot ID   A0A249A0I8
Organism   Mannheimia haemolytica strain Mh184.20180323.PV.F     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1117911..1129107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABJR17_RS05310 (ABJR17_001063) lptE 1119857..1120345 (+) 489 WP_006251337.1 LPS assembly lipoprotein LptE -
  ABJR17_RS05315 (ABJR17_001064) holA 1120388..1121413 (+) 1026 WP_006253426.1 DNA polymerase III subunit delta -
  ABJR17_RS05320 (ABJR17_001065) yacG 1121414..1121599 (-) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  ABJR17_RS05325 (ABJR17_001066) coaE 1121581..1122216 (-) 636 WP_020831305.1 dephospho-CoA kinase -
  ABJR17_RS05330 (ABJR17_001067) - 1122252..1122908 (-) 657 WP_006248404.1 prepilin peptidase -
  ABJR17_RS05335 (ABJR17_001068) pilC 1122911..1124107 (-) 1197 WP_006248403.1 type II secretion system F family protein Machinery gene
  ABJR17_RS05340 (ABJR17_001069) pilB 1124091..1125491 (-) 1401 WP_040080755.1 GspE/PulE family protein Machinery gene
  ABJR17_RS05345 (ABJR17_001070) pilA 1125512..1125991 (-) 480 WP_006248401.1 prepilin peptidase-dependent pilin Machinery gene
  ABJR17_RS05350 (ABJR17_001071) radA 1126172..1127551 (+) 1380 WP_040080753.1 DNA repair protein RadA Machinery gene
  ABJR17_RS05355 (ABJR17_001072) - 1127606..1127836 (-) 231 WP_006248398.1 YgjV family protein -
  ABJR17_RS05360 (ABJR17_001073) folA 1127956..1128449 (-) 494 Protein_1030 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 45186.75 Da        Isoelectric Point: 9.4698

>NTDB_id=1050880 ABJR17_RS05335 WP_006248403.1 1122911..1124107(-) (pilC) [Mannheimia haemolytica strain Mh184.20180323.PV.F]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=1050880 ABJR17_RS05335 WP_006248403.1 1122911..1124107(-) (pilC) [Mannheimia haemolytica strain Mh184.20180323.PV.F]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGCTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTCTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGTGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A249A0I8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

54

100

0.543
  pilC Haemophilus influenzae Rd KW20

42.145

100

0.425
  pilC Haemophilus influenzae 86-028NP

41.147

100

0.415

Multiple sequence alignment