Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ABJR11_RS06495 Genome accession   NZ_CP169354
Coordinates   1355756..1356952 (-) Length   398 a.a.
NCBI ID   WP_006248403.1    Uniprot ID   A0A249A0I8
Organism   Mannheimia haemolytica strain Mh184.20180323.PV.H     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1350756..1361952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABJR11_RS06470 (ABJR11_001294) lptE 1352702..1353190 (+) 489 WP_006251337.1 LPS assembly lipoprotein LptE -
  ABJR11_RS06475 (ABJR11_001295) holA 1353233..1354258 (+) 1026 WP_006253426.1 DNA polymerase III subunit delta -
  ABJR11_RS06480 (ABJR11_001296) yacG 1354259..1354444 (-) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  ABJR11_RS06485 (ABJR11_001297) coaE 1354426..1355061 (-) 636 WP_020831305.1 dephospho-CoA kinase -
  ABJR11_RS06490 (ABJR11_001298) - 1355097..1355753 (-) 657 WP_006248404.1 prepilin peptidase -
  ABJR11_RS06495 (ABJR11_001299) pilC 1355756..1356952 (-) 1197 WP_006248403.1 type II secretion system F family protein Machinery gene
  ABJR11_RS06500 (ABJR11_001300) pilB 1356936..1358336 (-) 1401 WP_040080755.1 GspE/PulE family protein Machinery gene
  ABJR11_RS06505 (ABJR11_001301) pilA 1358357..1358836 (-) 480 WP_006248401.1 prepilin peptidase-dependent pilin Machinery gene
  ABJR11_RS06510 (ABJR11_001302) radA 1359017..1360396 (+) 1380 WP_040080753.1 DNA repair protein RadA Machinery gene
  ABJR11_RS06515 (ABJR11_001303) - 1360451..1360681 (-) 231 WP_006248398.1 YgjV family protein -
  ABJR11_RS06520 (ABJR11_001304) folA 1360801..1361295 (-) 495 WP_006248397.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 45186.75 Da        Isoelectric Point: 9.4698

>NTDB_id=1050821 ABJR11_RS06495 WP_006248403.1 1355756..1356952(-) (pilC) [Mannheimia haemolytica strain Mh184.20180323.PV.H]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=1050821 ABJR11_RS06495 WP_006248403.1 1355756..1356952(-) (pilC) [Mannheimia haemolytica strain Mh184.20180323.PV.H]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGCTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTCTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGTGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A249A0I8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

54

100

0.543
  pilC Haemophilus influenzae Rd KW20

42.145

100

0.425
  pilC Haemophilus influenzae 86-028NP

41.147

100

0.415

Multiple sequence alignment