Detailed information NTG1043715

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACD268_RS06315
• Genome accession: NZ_CP168299
• Coordinates: 1238221..1239174 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain FC1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1233221..1244174

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD268_RS06290 (ACD268_06290)	-	1233711..1233806 (-)	96	Protein_1245	IS630 family transposase	-
ACD268_RS06295 (ACD268_06295)	-	1234219..1234560 (+)	342	Protein_1246	transposase	-
ACD268_RS06300 (ACD268_06300)	prsA	1234677..1235618 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
ACD268_RS06305 (ACD268_06305)	-	1235685..1236398 (-)	714	WP_000230399.1	O-methyltransferase	-
ACD268_RS06310 (ACD268_06310)	pepF	1236400..1238202 (-)	1803	WP_330789246.1	oligoendopeptidase F	Regulator
ACD268_RS06315 (ACD268_06315)	coiA	1238221..1239174 (-)	954	WP_000495911.1	competence protein CoiA	Machinery gene
ACD268_RS06320 (ACD268_06320)	tehB	1239247..1240107 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
ACD268_RS06325 (ACD268_06325)	smpB	1240123..1240590 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
ACD268_RS06330 (ACD268_06330)	rnr	1240553..1242907 (-)	2355	WP_050096418.1	ribonuclease R	-
ACD268_RS06335 (ACD268_06335)	secG	1243009..1243242 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
ACD268_RS06340 (ACD268_06340)	rpmG	1243282..1243431 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=1043715 ACD268_RS06315 WP_000495911.1 1238221..1239174(-) (coiA) [Streptococcus pneumoniae strain FC1]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1043715 ACD268_RS06315 WP_000495911.1 1238221..1239174(-) (coiA) [Streptococcus pneumoniae strain FC1]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435