Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   ACD269_RS09850 Genome accession   NZ_CP168260
Coordinates   1901721..1902134 (-) Length   137 a.a.
NCBI ID   WP_000265615.1    Uniprot ID   C1CA94
Organism   Streptococcus pneumoniae strain FC2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1896721..1907134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS09825 (ACD269_09825) - 1896965..1897096 (-) 132 WP_000768904.1 hypothetical protein -
  ACD269_RS09830 (ACD269_09830) - 1897097..1898287 (-) 1191 WP_000167770.1 acetate kinase -
  ACD269_RS09835 (ACD269_09835) comYH 1898338..1899291 (-) 954 WP_000345132.1 class I SAM-dependent methyltransferase Machinery gene
  ACD269_RS09840 (ACD269_09840) - 1899637..1900439 (+) 803 Protein_1913 IS5 family transposase -
  ACD269_RS09845 (ACD269_09845) - 1900590..1901066 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  ACD269_RS09850 (ACD269_09850) comGG/cglG 1901721..1902134 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACD269_RS09855 (ACD269_09855) comGF/cglF 1902112..1902573 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACD269_RS09860 (ACD269_09860) comGE/cglE 1902536..1902838 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACD269_RS09865 (ACD269_09865) comGD/cglD 1902801..1903235 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACD269_RS09870 (ACD269_09870) comGC/cglC 1903198..1903521 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  ACD269_RS09875 (ACD269_09875) comGB/cglB 1903523..1904539 (-) 1017 WP_078141518.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACD269_RS09880 (ACD269_09880) comGA/cglA/cilD 1904487..1905428 (-) 942 WP_000249572.1 competence type IV pilus ATPase ComGA Machinery gene
  ACD269_RS09885 (ACD269_09885) - 1905504..1905869 (-) 366 WP_000286415.1 DUF1033 family protein -
  ACD269_RS09890 (ACD269_09890) - 1906020..1907078 (-) 1059 WP_000649465.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 15888.28 Da        Isoelectric Point: 10.1695

>NTDB_id=1043528 ACD269_RS09850 WP_000265615.1 1901721..1902134(-) (comGG/cglG) [Streptococcus pneumoniae strain FC2]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNKEKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKK
TSLVTTVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=1043528 ACD269_RS09850 WP_000265615.1 1901721..1902134(-) (comGG/cglG) [Streptococcus pneumoniae strain FC2]
GTGTGGAAAAAGAAGAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTACA
ATTTTACTTGAACCGACAAATCGCCCACTATCAAGACTATGCTTTAAATAAAGAAAAGTTGGTTGCTTTTGCCATGGCCA
AGCGAACCAAGGATAAAGCCGAGCAAGAAAGTGGGGAACAGGTCTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACAAGCTTGGTGACGACTGTTCGTACGGATAAGAGTCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACTGATTCAAGCGAAAAAGCGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCCTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB C1CA94

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus mitis SK321

86.861

100

0.869

  comGG/cglG Streptococcus pneumoniae Rx1

95.726

85.401

0.818

  comGG/cglG Streptococcus pneumoniae D39

95.726

85.401

0.818

  comGG/cglG Streptococcus pneumoniae R6

95.726

85.401

0.818

  comGG/cglG Streptococcus pneumoniae TIGR4

95.726

85.401

0.818

  comGG/cglG Streptococcus mitis NCTC 12261

89.344

89.051

0.796

  comYG Streptococcus mutans UA140

38.806

97.81

0.38

  comYG Streptococcus mutans UA159

38.806

97.81

0.38


Multiple sequence alignment