Detailed information NTG1043508

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ACD269_RS08535
• Genome accession: NZ_CP168260
• Coordinates: 1678372..1679031 (+)
• Length: 219 a.a.
• NCBI ID: WP_373380504.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FC2
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1673372..1684031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD269_RS08500 (ACD269_08500)	mgaSpn	1673981..1675462 (-)	1482	WP_373380502.1	virulence factor transcriptional regulator MgaSpn	-
ACD269_RS08505 (ACD269_08505)	-	1675846..1676070 (+)	225	WP_223200767.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
ACD269_RS08510 (ACD269_08510)	amaP	1676154..1676720 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
ACD269_RS08515 (ACD269_08515)	-	1676732..1676902 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
ACD269_RS08520 (ACD269_08520)	-	1676941..1677549 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
ACD269_RS08525 (ACD269_08525)	-	1677580..1677783 (+)	204	WP_000109956.1	CsbD family protein	-
ACD269_RS08530 (ACD269_08530)	-	1677856..1678302 (-)	447	WP_000155416.1	GNAT family N-acetyltransferase	-
ACD269_RS08535 (ACD269_08535)	cclA/cilC	1678372..1679031 (+)	660	WP_373380504.1	A24 family peptidase	Machinery gene
ACD269_RS08540 (ACD269_08540)	-	1679083..1680234 (-)	1152	WP_050210547.1	XRE family transcriptional regulator	-
ACD269_RS08545 (ACD269_08545)	-	1680249..1680978 (-)	730	Protein_1691	hypothetical protein	-
ACD269_RS08550 (ACD269_08550)	-	1681198..1681308 (+)	111	Protein_1692	prepilin peptidase	-
ACD269_RS08555 (ACD269_08555)	trpA	1681280..1682056 (-)	777	WP_373380505.1	tryptophan synthase subunit alpha	-
ACD269_RS08560 (ACD269_08560)	trpB	1682049..1683272 (-)	1224	WP_373380507.1	tryptophan synthase subunit beta	-
ACD269_RS08565 (ACD269_08565)	-	1683250..1683849 (-)	600	WP_000169894.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24979.13 Da
• Isoelectric Point: 7.9675

>NTDB_id=1043508 ACD269_RS08535 WP_373380504.1 1678372..1679031(+) (cclA/cilC) [Streptococcus pneumoniae strain FC2]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLRQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=1043508 ACD269_RS08535 WP_373380504.1 1678372..1679031(+) (cclA/cilC) [Streptococcus pneumoniae strain FC2]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGAGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae D39	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae R6	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae TIGR4	97.26	100	0.973
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863