Detailed information NTG1040760

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACDW35_RS25995
• Genome accession: NZ_CP167983
• Coordinates: 5574898..5576235 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 0102d1_7
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5569898..5581235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDW35_RS25970 (ACDW35_25970)	pgeF	5570041..5570769 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
ACDW35_RS25975 (ACDW35_25975)	rluD	5570766..5571728 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACDW35_RS25980 (ACDW35_25980)	-	5571874..5572899 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACDW35_RS25985 (ACDW35_25985)	-	5573056..5573301 (+)	246	WP_003102591.1	PP0621 family protein	-
ACDW35_RS25990 (ACDW35_25990)	pilS	5573291..5574883 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACDW35_RS25995 (ACDW35_25995)	pilR	5574898..5576235 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACDW35_RS26000 (ACDW35_26000)	thiO	5576281..5577375 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
ACDW35_RS26005 (ACDW35_26005)	-	5577515..5578015 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
ACDW35_RS26010 (ACDW35_26010)	-	5578138..5578626 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
ACDW35_RS26015 (ACDW35_26015)	pilV	5578636..5579160 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
ACDW35_RS26020 (ACDW35_26020)	-	5579169..5579984 (+)	816	WP_016254061.1	PilW family protein	-
ACDW35_RS26025 (ACDW35_26025)	-	5579981..5580586 (+)	606	WP_003116263.1	PilX N-terminal domain-containing pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1040760 ACDW35_RS25995 WP_003094694.1 5574898..5576235(+) (pilR) [Pseudomonas aeruginosa strain 0102d1_7]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1040760 ACDW35_RS25995 WP_003094694.1 5574898..5576235(+) (pilR) [Pseudomonas aeruginosa strain 0102d1_7]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTACGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384