Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   ACDK45_RS09365 Genome accession   NZ_CP167879
Coordinates   1875224..1875916 (-) Length   230 a.a.
NCBI ID   WP_038440789.1    Uniprot ID   A0AAJ8WR53
Organism   Haemophilus influenzae strain NTHi52     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1870224..1880916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACDK45_RS09330 (ACDK45_09330) - 1871785..1871991 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACDK45_RS09335 (ACDK45_09335) - 1872077..1872283 (-) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  ACDK45_RS09340 (ACDK45_09340) - 1872369..1872575 (-) 207 WP_005648955.1 heavy-metal-associated domain-containing protein -
  ACDK45_RS09345 (ACDK45_09345) - 1872661..1872867 (-) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  ACDK45_RS09350 (ACDK45_09350) cueR 1872944..1873330 (+) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  ACDK45_RS09355 (ACDK45_09355) metJ 1873344..1873661 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  ACDK45_RS09360 (ACDK45_09360) rho 1873909..1875170 (+) 1262 Protein_1785 transcription termination factor Rho -
  ACDK45_RS09365 (ACDK45_09365) pilD 1875224..1875916 (-) 693 WP_038440789.1 A24 family peptidase Machinery gene
  ACDK45_RS09370 (ACDK45_09370) pilC 1875913..1877133 (-) 1221 WP_011271971.1 type II secretion system F family protein Machinery gene
  ACDK45_RS09375 (ACDK45_09375) pilB 1877130..1878524 (-) 1395 WP_044364868.1 GspE/PulE family protein Machinery gene
  ACDK45_RS09380 (ACDK45_09380) pilA 1878521..1878970 (-) 450 WP_044364865.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  ACDK45_RS09385 (ACDK45_09385) ampD 1879085..1879639 (+) 555 WP_044364862.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26786.77 Da        Isoelectric Point: 8.6895

>NTDB_id=1040096 ACDK45_RS09365 WP_038440789.1 1875224..1875916(-) (pilD) [Haemophilus influenzae strain NTHi52]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1040096 ACDK45_RS09365 WP_038440789.1 1875224..1875916(-) (pilD) [Haemophilus influenzae strain NTHi52]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

97.391

100

0.974
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment