Detailed information NTG1037585

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACB351_RS03495
• Genome accession: NZ_CP167015
• Coordinates: 690893..692122 (+)
• Length: 409 a.a.
• NCBI ID: WP_047298102.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 11
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 685893..697122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB351_RS03475 (ACB351_03475)	-	686509..687786 (-)	1278	WP_011284699.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACB351_RS03480 (ACB351_03480)	-	687773..688948 (-)	1176	WP_021340971.1	hydroxymethylglutaryl-CoA synthase	-
ACB351_RS03485 (ACB351_03485)	-	689157..689996 (+)	840	WP_011017679.1	thymidylate synthase	-
ACB351_RS03490 (ACB351_03490)	-	690076..690573 (+)	498	WP_011284701.1	dihydrofolate reductase	-
ACB351_RS03495 (ACB351_03495)	clpX	690893..692122 (+)	1230	WP_047298102.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACB351_RS03500 (ACB351_03500)	yihA	692132..692731 (+)	600	WP_011284702.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ACB351_RS03505 (ACB351_03505)	-	692879..693622 (+)	744	WP_002984942.1	hypothetical protein	-
ACB351_RS03510 (ACB351_03510)	-	693680..695779 (-)	2100	WP_011284703.1	AAA family ATPase	-
ACB351_RS03515 (ACB351_03515)	rpiA	696157..696840 (+)	684	WP_011284704.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45021.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=1037585 ACB351_RS03495 WP_047298102.1 690893..692122(+) (clpX) [Streptococcus pyogenes strain Isolate 11]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFTIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1037585 ACB351_RS03495 WP_047298102.1 690893..692122(+) (clpX) [Streptococcus pyogenes strain Isolate 11]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTACTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAGCGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572